Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2309241 | 0.78 | ALDH1A1 (0.50) | ALDH1A1MAPTKDM4ESMN1; SMN2LMNA | |
| Bromide SCHEMBL29136390 | 0.77 | ALDH1A1 (0.49) | ALDH1A1MAPTKDM4ESMN1; SMN2LMNA | |
| SCHEMBL21268021 | 0.71 | ALDH1A1 (0.48) | ALDH1A1MAPTKDM4ESMN1; SMN2LMNA | |
| SCHEMBL29791776 | 0.65 | ALDH1A1 (0.59) | ALDH1A1KDM4EHSD17B10KMT2A | |
| SCHEMBL19873363 | 0.65 | ALDH1A1 (0.43) | ALDH1A1MAPTKDM4ELMNAHTT | |
| SCHEMBL6770346 | 0.64 | ALDH1A1 (0.53) | ALDH1A1MAPTKDM4ESMN1; SMN2LMNA | |
| SCHEMBL631497 | 0.64 | ALDH1A1 (0.48) | ALDH1A1MAPTKDM4ESMN1; SMN2LMNA | |
| SCHEMBL2272050 | 0.62 | ALDH1A1 (0.47) | ALDH1A1MAPTKDM4ELMNAHSD17B10 | |
| SCHEMBL4820959 | 0.62 | ALDH1A1 (0.55) | ALDH1A1MAPTKDM4ESMN1; SMN2LMNA | |
| SCHEMBL23915341 | 0.61 | MAOB (0.40) | ALDH1A1MAPTKDM4EHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021220120-A1 | NOVEL COMPOUNDS USEFUL AS POLY(ADP-RIBOSE) POLYMERASE (PARP) INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2021-11-04 | — | — | WO | disclosed |