Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8244205 | 1.00 | KMT2A (0.44) | KMT2AMEN1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL24595901 | 0.83 | KMT2A (0.41) | KMT2AMEN1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL25734938 | 0.81 | L3MBTL1 (0.45) | KMT2AMEN1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL1006031 | 0.76 | ALDH1A1 (0.53) | KMT2AMEN1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL13495380 | 0.76 | KMT2A (0.45) | KMT2AMEN1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL107824 | 0.76 | L3MBTL1 (0.44) | KMT2AMEN1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL15172849 | 0.75 | L3MBTL1 (0.43) | KMT2AMEN1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL1537360 | 0.73 | HTT (0.39) | KMT2AALDH1A1KDM4ECYP1A2GAA | |
| SCHEMBL5865692 | 0.73 | POLB (0.34) | — | |
| SCHEMBL18840159 | 0.73 | HTT (0.36) | KMT2AALDH1A1KDM4ECYP1A2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022061168-A1 | E-SELECTIN TARGETING AGENTS | GLYCOMIMETICS, INC. (US) | 2022-03-24 | — | — | WO | disclosed |
| WO-2021222777-A1 | CD33 LIGANDS SUITABLE FOR INCORPORATION INTO CARRIERS | MAGNANI JOHN L (US) | 2021-11-04 | — | — | WO | disclosed |
| WO-2021222767-A1 | CD33 LIGANDS SUITABLE FOR INCORPORATION INTO CARRIERS | GLYCOMIMETICS, INC. (US) | 2021-11-04 | — | — | WO | disclosed |