Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 7/20 | 1.00 |
| ▸ | PGR | P06401 | 4/20 | 0.78 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.78 |
| ▸ | HRH1 | P35367 | 1/20 | 0.78 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.73 |
| ▸ | AR | P10275 | 3/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | FNTA | P49354 | 1/20 | 0.68 |
| ▸ | FNTB | P49356 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.58 |
| ▸ | SHBG | P04278 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fludrocortisone SCHEMBL10598529 | 1.00 | NR3C1 (1.00) | NR3C1PGRHIF1AHRH1SERPINA6 | |
| Fludrocortisone SCHEMBL19327146 | 1.00 | NR3C1 (1.00) | NR3C1PGRHIF1AHRH1SERPINA6 | |
| Fludrocortisone SCHEMBL5188889 | 1.00 | NR3C1 (1.00) | NR3C1PGRHIF1AHRH1SERPINA6 | |
| Fludrocortisone SCHEMBL14373312 | 1.00 | NR3C1 (1.00) | NR3C1PGRHIF1AHRH1SERPINA6 | |
| Fludrocortisone SCHEMBL4323075 | 1.00 | NR3C1 (1.00) | NR3C1PGRHIF1AHRH1SERPINA6 | |
| Fludrocortisone SCHEMBL13026141 | 1.00 | NR3C1 (1.00) | NR3C1PGRHIF1AHRH1SERPINA6 | |
| Fludrocortisone SCHEMBL4545 | 1.00 | NR3C1 (1.00) | NR3C1PGRHIF1AHRH1SERPINA6 | |
| Fludrocortisone SCHEMBL21297043 | 0.98 | NR3C1 (0.96) | NR3C1PGRHIF1AHRH1SERPINA6 | |
| SCHEMBL8735123 | 0.93 | NR3C1 (0.87) | NR3C1PGRHIF1AHRH1SERPINA6 | |
| SCHEMBL8735124 | 0.93 | NR3C1 (0.87) | NR3C1PGRHIF1AHRH1SERPINA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021220061-A2 | HETERODIMER COMPOSITIONS AND METHODS FOR THE TREATMENT OF OCULAR DISORDERS | RIPPLE THERAPEUTICS CORPORATION (CA) | 2021-11-04 | — | — | WO | disclosed |