Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 5/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23977291 | 0.78 | GRM5 (0.32) | MAPTHPGD | |
| SCHEMBL20373738 | 0.77 | GBA1 (0.42) | GBA1ALDH1A1MBOAT4GRM2SMN1; SMN2 | |
| SCHEMBL20387984 | 0.75 | SYK (0.52) | ALDH1A1MAPTSMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL23977388 | 0.74 | ALDH1A1 (0.40) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL1855342 | 0.71 | GBA1 (0.46) | GBA1ALDH1A1MBOAT4MAPTGRM2 | |
| SCHEMBL17664387 | 0.70 | KEAP1 (0.43) | GBA1ALDH1A1MBOAT4MAPTGRM2 | |
| SCHEMBL1816193 | 0.68 | GBA1 (0.47) | GBA1ALDH1A1MBOAT4MAPTGRM2 | |
| SCHEMBL11926924 | 0.68 | GBA1 (0.41) | GBA1ALDH1A1MBOAT4GRM2SMN1; SMN2 | |
| SCHEMBL2515176 | 0.67 | GBA1 (0.42) | GBA1ALDH1A1MBOAT4GRM2SMN1; SMN2 | |
| SCHEMBL15510613 | 0.66 | ACHE (0.40) | ALDH1A1MAPTHPGDDRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021219813-A1 | ANTIBACTERIAL AND ANTIFUNGAL PLEUROMUTILIN CONJUGATES | SYDDANSK UNIVERSITET (DK) | 2021-11-04 | — | — | WO | disclosed |