Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.43 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21756757 | 0.82 | ALDH1A1 (0.42) | CNR2NUDT1MEN1KMT2AL3MBTL1 | |
| SCHEMBL25510504 | 0.80 | CYP2C19 (0.36) | CNR2MEN1KMT2AL3MBTL1LMNA | |
| Hydrochloric Acid SCHEMBL29072765 | 0.78 | CNR2 (0.48) | CNR2SSTR4NUDT1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL30117102 | 0.78 | CNR2 (0.45) | CNR2NUDT1MEN1KMT2AL3MBTL1 | |
| SCHEMBL14152072 | 0.77 | CNR2 (0.63) | CNR2MEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL20057276 | 0.77 | SSTR4 (0.52) | CNR2SSTR4 | |
| SCHEMBL15350504 | 0.77 | L3MBTL1 (0.43) | CNR2MEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL17707924 | 0.76 | GRM5 (0.42) | SSTR4MEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL4826271 | 0.76 | S1PR4 (0.42) | CNR2LMNAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL17433349 | 0.76 | SSTR4 (0.36) | SSTR4KMT2AALDH1A1MBOAT4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230136562-A1 | SPIROUREA DERIVATIVES | IDORSIA PHARMACEUTICALS LTD (CH) | 2023-05-04 | — | — | US | disclosed |
| WO-2023014908-A1 | LPAR1 ANTAGONISTS AND USES THEREOF | Pipeline Therapeutics, Inc. (US) | 2023-02-09 | — | — | WO | disclosed |
| WO-2021219594-A1 | SPIROUREA DERIVATIVES | IDORSIA PHARMACEUTICALS LTD (CH) | 2021-11-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230136562-A1 | SPIROUREA DERIVATIVES | KCNA7, PKD2, KCNN3 | CNR2 1402/4885SSTR4 763/4885NUDT1 2301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.