Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA2 | P47869 | 2/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23978211 | 0.85 | — | — | |
| SCHEMBL23978092 | 0.72 | — | — | |
| SCHEMBL23960285 | 0.70 | MPL (0.32) | — | |
| SCHEMBL23960271 | 0.70 | MEN1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL23927267 | 0.68 | MPL (0.31) | — | |
| SCHEMBL18419789 | 0.67 | CTSS (0.38) | GABRA2GABRB2ARCTSSCTSK | |
| SCHEMBL16941916 | 0.67 | HSD11B1 (0.41) | CTSSCTSK | |
| SCHEMBL10061561 | 0.66 | ALDH1A1 (0.41) | CTSSCTSK | |
| SCHEMBL7931296 | 0.65 | AR (0.38) | ARCTSK | |
| SCHEMBL19018008 | 0.64 | CTSK (0.36) | GABRA2GABRB2GABRB3ARCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021219731-A2 | BICYCLIC KINASE INHIBITORS AND USES THEREOF | IOMX THERAPEUTICS AG (DE) | 2021-11-04 | — | — | WO | disclosed |