Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 4/20 | 0.39 |
| ▸ | GLS | O94925 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23978812 | 0.84 | CTSL (0.45) | CTSLKCNQ2GLSKDM4ESYK | |
| SCHEMBL26103779 | 0.84 | CTSL (0.45) | CTSLKCNQ2GLSKDM4ESYK | |
| SCHEMBL30279367 | 0.84 | CTSL (0.45) | CTSLKCNQ2GLSKDM4ESYK | |
| SCHEMBL23979131 | 0.80 | KCNQ2 (0.39) | KCNQ2MEN1KMT2AALDH1A1MAPK8 | |
| SCHEMBL24805443 | 0.78 | CTSL (0.43) | CTSLKCNQ2GLSKDM4EANO1 | |
| SCHEMBL23978985 | 0.76 | SLC1A3 (0.38) | KCNQ2GLSMEN1KMT2A | |
| SCHEMBL1185574 | 0.74 | CTSL (0.59) | CTSLKDM4ESYKMEN1KMT2A | |
| SCHEMBL30336898 | 0.73 | KCNQ2 (0.54) | KCNQ2KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL23978834 | 0.73 | KCNQ2 (0.54) | KCNQ2KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL23978894 | 0.72 | KCNQ2 (0.54) | KCNQ2MEN1KMT2AALDH1A1MAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222789-A1 | INHIBITORS OF ALPHA 2 BETA 1 INTEGRIN AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-11-04 | — | — | WO | disclosed |