Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ2 | O43526 | 4/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23978832 | 0.82 | KCNQ2 (0.43) | KCNQ2EPHX2MAPK8MAPK9MEN1 | |
| SCHEMBL23978987 | 0.80 | CTSL (0.40) | KCNQ2MAPK8MEN1KMT2AALDH1A1 | |
| SCHEMBL23978639 | 0.78 | KCNQ2 (0.42) | KCNQ2EPHX2MAPK8MEN1KMT2A | |
| SCHEMBL23978985 | 0.78 | SLC1A3 (0.38) | KCNQ2MEN1KMT2ALMNAMAPT | |
| SCHEMBL23978894 | 0.73 | KCNQ2 (0.54) | KCNQ2EPHX2MAPK8MEN1KMT2A | |
| SCHEMBL23978674 | 0.73 | KCNQ2 (0.56) | KCNQ2EPHX2MAPK8MEN1KMT2A | |
| SCHEMBL30336898 | 0.72 | KCNQ2 (0.54) | KCNQ2EPHX2MAPK8MEN1KMT2A | |
| SCHEMBL23978834 | 0.72 | KCNQ2 (0.54) | KCNQ2EPHX2MAPK8MEN1KMT2A | |
| SCHEMBL24803414 | 0.70 | KCNQ2 (0.47) | KCNQ2EPHX2MAPK8MEN1KMT2A | |
| SCHEMBL23978676 | 0.69 | KDM4E (0.33) | KMT2AALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222789-A1 | INHIBITORS OF ALPHA 2 BETA 1 INTEGRIN AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-11-04 | — | — | WO | disclosed |