Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.34 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.34 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.32 |
| ▸ | GLS | O94925 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23979131 | 0.78 | KCNQ2 (0.39) | MEN1KMT2ALMNAMAPTKCNQ2 | |
| SCHEMBL23978694 | 0.78 | CA12 (0.46) | SLC1A3SLC1A2SLC1A1CA12CA1 | |
| SCHEMBL23978987 | 0.76 | CTSL (0.40) | MEN1KMT2AKCNQ2GLS | |
| SCHEMBL26497251 | 0.65 | KCNQ2 (0.38) | CA1CA2KCNJ5KCNJ3MEN1 | |
| SCHEMBL23978667 | 0.65 | SMN1; SMN2 (0.48) | MEN1KMT2ALMNAMAPTHTT | |
| SCHEMBL23978639 | 0.65 | KCNQ2 (0.42) | MEN1KMT2AKCNQ2 | |
| SCHEMBL23978676 | 0.64 | KDM4E (0.33) | KMT2ALMNA | |
| SCHEMBL23978834 | 0.64 | KCNQ2 (0.54) | CA1CA2MEN1KMT2AL3MBTL1 | |
| SCHEMBL30336898 | 0.64 | KCNQ2 (0.54) | CA1CA2MEN1KMT2AL3MBTL1 | |
| SCHEMBL23978654 | 0.63 | ALDH1A1 (0.42) | MEN1KMT2AMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222789-A1 | INHIBITORS OF ALPHA 2 BETA 1 INTEGRIN AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-11-04 | — | — | WO | disclosed |