Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CTSV | O60911 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23978696 | 0.90 | TACR1 (0.46) | NPC1SMN1; SMN2MEN1HCRTR1KMT2A | |
| SCHEMBL23979030 | 0.88 | NPC1 (0.46) | NPC1MEN1HCRTR1KMT2ACTSV | |
| SCHEMBL30083833 | 0.81 | TAS1R3 (0.42) | LMNASMN1; SMN2EPHX2 | |
| SCHEMBL23978623 | 0.81 | TAS1R3 (0.42) | LMNASMN1; SMN2EPHX2 | |
| SCHEMBL24805474 | 0.81 | TAS1R3 (0.42) | LMNASMN1; SMN2EPHX2 | |
| SCHEMBL23979042 | 0.81 | TAS1R3 (0.42) | LMNASMN1; SMN2EPHX2 | |
| SCHEMBL26484598 | 0.79 | TAOK1 (0.39) | LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL26507224 | 0.79 | LMNA (0.39) | NPC1LMNASMN1; SMN2THRBEPHX2 | |
| SCHEMBL23978995 | 0.78 | TACR1 (0.42) | NPC1SMN1; SMN2MEN1HCRTR1KMT2A | |
| SCHEMBL26502639 | 0.78 | TACR1 (0.42) | NPC1SMN1; SMN2MEN1HCRTR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222789-A1 | INHIBITORS OF ALPHA 2 BETA 1 INTEGRIN AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-11-04 | — | — | WO | disclosed |