Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.45 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 2/20 | 0.42 |
| ▸ | RXRB | P28702 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | CCR9 | P51686 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12993133 | 0.85 | RXRA (0.58) | ACHERXRARXRBCYP2C19CYP1A2 | |
| SCHEMBL15032898 | 0.85 | ALDH1A1 (0.56) | ACHEHDAC4HDAC2HDAC8RXRA | |
| SCHEMBL12993402 | 0.83 | CYP1A2 (0.45) | ACHEHDAC4HDAC2HDAC8RXRA | |
| SCHEMBL23979331 | 0.83 | CYP1A2 (0.51) | ACHEHDAC4HDAC2HDAC8RXRA | |
| SCHEMBL19169511 | 0.81 | DRD2 (0.50) | CYP24A1 | |
| SCHEMBL12993003 | 0.81 | SIRT2 (0.49) | ACHEHDAC4HDAC2HDAC8CYP2C19 | |
| SCHEMBL12993335 | 0.81 | CYP2C19 (0.46) | ACHEHDAC4HDAC2HDAC8CYP2C19 | |
| SCHEMBL12993388 | 0.81 | KMT2A (0.44) | ACHEHDAC4HDAC2HDAC8RXRA | |
| SCHEMBL11203907 | 0.80 | MAOA (0.50) | CYP24A1 | |
| SCHEMBL26343269 | 0.80 | TAAR1 (0.49) | CYP24A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210338670-A1 | NON-INVASIVE PET IMAGING OF CDK4/6 ACTIVATION IN CANCER | NEW YORK UNIVERSITY | 2021-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210338670-A1 | NON-INVASIVE PET IMAGING OF CDK4/6 ACTIVATION IN CANCER | CDK4, CDK6, CDKL4 | ACHE 4099/4885CYP24A1 1557/4885HDAC4 107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.