Fluoride Ion

Fluoride Ion

SCHEMBL2398102

COC(=O)CC[N+](C)(C)Cc1ccccc1.[F-]

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.53
KDM4E B2RXH2 2/20 0.53
LMNA P02545 1/20 0.53
DNM1 Q05193 2/20 0.46
CA12 O43570 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
SMN1; SMN2 Q16637 3/20 0.45
TP53 P04637 1/20 0.45
MAPK1 P28482 1/20 0.45
HTT P42858 3/20 0.44
LTA4H P09960 1/20 0.42
MAPT P10636 2/20 0.41
RAB9A P51151 2/20 0.41
AKT1 P31749 1/20 0.41
CYP11B1 P15538 1/20 0.41
CYP11B2 P19099 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15637262 0.80 ALDH1A1 (0.55) ALDH1A1KDM4EDNM1MEN1KMT2A
SCHEMBL10892321 0.78 HDAC3 (0.53) ALDH1A1KDM4EDNM1MEN1KMT2A
Hydrochloric Acid SCHEMBL11664988 0.75 TDP1 (0.54) ALDH1A1KDM4ELMNADNM1MEN1
Hydrogen Sulfide SCHEMBL28016697 0.75 ALDH1A1 (0.61) ALDH1A1KDM4ELMNAMEN1KMT2A
Hydrochloric Acid SCHEMBL7853055 0.74 MEN1 (0.49) ALDH1A1KDM4EDNM1MEN1KMT2A
SCHEMBL16353097 0.74 ALDH1A1 (0.54) ALDH1A1DNM1MEN1KMT2ASMN1; SMN2
SCHEMBL5963139 0.74 DNM1 (0.67) ALDH1A1KDM4ELMNADNM1MEN1
SCHEMBL162806 0.74 HDAC1 (0.62) ALDH1A1KDM4ELMNACA12CA7
SCHEMBL16353101 0.74 TDP1 (0.50) ALDH1A1LMNADNM1MEN1KMT2A
SCHEMBL13702211 0.73 ALDH1A1 (0.62) ALDH1A1KDM4ELMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3972698-B1 ORAL COMPOSITIONS AND METHODS OF USE SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2025-02-12 EP disclosed
EP-3463584-B1 THERAPEUTIC DENTAL PASTES AND THE APPLICATION THEREOF 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-12-27 EP disclosed
US-20230293393-A1 NATURAL TOOTH POWDER TABLETS MCCORMICK LINDSAY (US) 2023-09-21 US disclosed
US-11701306-B2 Natural tooth powder tablets MCCORMICK LINDSAY (US) 2023-07-18 US disclosed
US-11696879-B2 Therapeutic dental pastes and related methods and kits 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-07-11 US disclosed
US-20220211603-A1 Oral Compositions And Methods Of Use SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2022-07-07 US disclosed
US-20220192953-A1 Oral Compositions And Methods Of Use 3M INNOVATIVE PROPERTIES COMPANY 2022-06-23 US disclosed
EP-3972698-A1 ORAL COMPOSITIONS AND METHODS OF USE 3M Innovative Properties Company (US) 2022-03-30 EP disclosed
EP-3972557-A1 ORAL COMPOSITIONS AND METHODS OF USE 3M Innovative Properties Company (US) 2022-03-30 EP disclosed
CN-113840635-A Oral compositions and methods of use 3M创新有限公司 2021-12-24 CN disclosed
EP-0249398-A2 Oral compositions THE PROCTER & GAMBLE COMPANY (US) 1987-12-16 EP disclosed
US-4684518-A ANTICALCULUS, PYROPHOSPHATE AND FLUORIDE THE PROCTER & GAMBLE COMPANY (US) 1987-08-04 US disclosed
US-4590066-A DENTRIFRICE CONTAINING PYROPHOSPHATES THE PROCTER & GAMBLE COMPANY (US) 1986-05-20 US disclosed
US-4515772-A ANTICARIES TOOTHPASTE THE PROCTER & GAMBLE COMPANY (US) 1985-05-07 US disclosed
EP-0097476-A2 Oral compositions THE PROCTER & GAMBLE COMPANY (US) 1984-01-04 EP disclosed
US-4051234-A BIS-GUANIDINE COMPOUND, ETHYLENEDIAMINEDIACETIC ACID OR SALT AS CHELATOR THE PROCTER & GAMBLE COMPANY (US) 1977-09-27 US disclosed
US-4025616-A Oral compositions for plaque, caries and calculus retardation with reduced staining tendencies THE PROCTER & GAMBLE COMPANY (US) 1977-05-24 US disclosed
US-3959458-A PHOSPHONATE OR AMINO-PHOSPHORUS COMPOUND THE PROCTER & GAMBLE COMPANY (US) 1976-05-25 US disclosed
US-3937807-A BISBIGUANIDE COMPOUND THE PROCTER & GAMBLE COMPANY (US) 1976-02-10 US disclosed
US-3934002-A BIS-GUANIDE THE PROCTER & GAMBLE COMPANY (US) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11696879-B2 Therapeutic dental pastes and related methods and kits PROC, DNASE1, COL2A1 ALDH1A1 1617/4885KDM4E 2674/4885LMNA 1536/4885
US-20220211603-A1 Oral Compositions And Methods Of Use MSR1, GCK, TAS2R40 ALDH1A1 4423/4885KDM4E 4231/4885LMNA 4241/4885
US-20220192953-A1 Oral Compositions And Methods Of Use HRH2, HRH3, HRH4 ALDH1A1 4776/4885KDM4E 3981/4885LMNA 4275/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.