Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 1/20 | 0.54 |
| ▸ | PRMT5 | O14744 | 18/20 | 0.48 |
| ▸ | WDR77 | Q9BQA1 | 17/20 | 0.48 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20938183 | 0.80 | ADK (0.58) | ADKPRMT5WDR77RAPGEF3 | |
| SCHEMBL20419288 | 0.80 | ADK (0.58) | ADKPRMT5WDR77RAPGEF3 | |
| SCHEMBL12150813 | 0.80 | ADK (0.58) | ADKPRMT5WDR77RAPGEF3 | |
| SCHEMBL23982356 | 0.80 | ADK (0.58) | ADKPRMT5WDR77RAPGEF3 | |
| SCHEMBL6731788 | 0.80 | ADK (0.58) | ADKPRMT5WDR77RAPGEF3 | |
| SCHEMBL12300483 | 0.80 | ADK (0.58) | ADKPRMT5WDR77RAPGEF3 | |
| SCHEMBL1738432 | 0.80 | ADK (0.58) | ADKPRMT5WDR77RAPGEF3 | |
| SCHEMBL20938420 | 0.80 | ADK (0.58) | ADKPRMT5WDR77RAPGEF3 | |
| SCHEMBL23982477 | 0.80 | AHCY (0.59) | — | |
| SCHEMBL14304624 | 0.80 | AHCY (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210338706-A1 | ADENOSINE ANALOG AND ITS USE IN REGULATING THE CIRCADIAN CLOCK | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2021-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210338706-A1 | ADENOSINE ANALOG AND ITS USE IN REGULATING THE CIRCADIAN CLOCK | PER2, CRY1, ADORA2A | ADK 4/4885PRMT5 1272/4885WDR77 285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.