Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.36 |
| ▸ | HPGDS | O60760 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2400368 | 0.87 | MAOA (0.39) | ALDH1A1HPGDSKDM4EACHEABCB1 | |
| SCHEMBL31018407 | 0.72 | L3MBTL1 (0.44) | ALDH1A1PLA2G4AHPGDSL3MBTL1KDM4E | |
| SCHEMBL31018413 | 0.70 | CA12 (0.44) | ALDH1A1PLA2G4AL3MBTL1KDM4EACHE | |
| SCHEMBL1502636 | 0.69 | L3MBTL1 (0.44) | ALDH1A1PLA2G4AHPGDSL3MBTL1KDM4E | |
| SCHEMBL30760182 | 0.67 | L3MBTL1 (0.43) | ALDH1A1PLA2G4AHPGDSL3MBTL1KDM4E | |
| SCHEMBL31018412 | 0.66 | L3MBTL1 (0.47) | ALDH1A1PLA2G4AHPGDSL3MBTL1KDM4E | |
| SCHEMBL27805949 | 0.65 | L3MBTL1 (0.40) | ALDH1A1PLA2G4AHPGDSL3MBTL1KDM4E | |
| SCHEMBL2213116 | 0.65 | L3MBTL1 (0.62) | L3MBTL1ABCB1 | |
| SCHEMBL23353906 | 0.65 | MMP13 (0.47) | PLA2G4AL3MBTL1MMP1MMP2MMP9 | |
| SCHEMBL1852466 | 0.65 | HDAC3 (0.52) | L3MBTL1KDM4EABCB1MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2380884-B1 | CARBOXYLIC ACID DERIVATIVE CONTAINING THIAZOLE RING AND PHARMACEUTICAL USE THEREOF | MITSUBISHI TANABE PHARMA CORP (JP) | 2014-02-12 | — | — | EP | disclosed |
| US-8497382-B2 | Carboxylic acid derivative containing thiazole ring and pharmaceutical use thereof | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2013-07-30 | — | — | US | disclosed |
| EP-2380884-A1 | CARBOXYLIC ACID DERIVATIVE CONTAINING THIAZOLE RING AND PHARMACEUTICAL USE THEREOF | Mitsubishi Tanabe Pharma Corporation (JP) | 2011-10-26 | — | — | EP | disclosed |
| US-20110237630-A1 | CARBOXYLIC ACID DERIVATIVE CONTAINING THIAZOLE RING AND PHARMACEUTICAL USE THEREOF | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2011-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110237630-A1 | CARBOXYLIC ACID DERIVATIVE CONTAINING THIAZOLE RING AND PHARMACEUTICAL USE THEREOF | PPARA, PPARD, PPARG | ALDH1A1 305/4885PLA2G4A 1350/4885HPGDS 1868/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.