SCHEMBL30760182

SCHEMBL30760182

O=C(O)c1csc(S(=O)(=O)Cl)n1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.43
ALDH1A1 P00352 2/20 0.41
KDM4E B2RXH2 2/20 0.41
PLA2G4A P47712 1/20 0.37
ACHE P22303 1/20 0.37
MMP1 P03956 1/20 0.37
MMP2 P08253 1/20 0.37
MMP9 P14780 1/20 0.37
MMP13 P45452 1/20 0.37
HPGDS O60760 1/20 0.37
PRKAG1 P54619 1/20 0.36
PRKAA2 P54646 1/20 0.36
PRKAB1 Q9Y478 1/20 0.36
POLB P06746 1/20 0.35
PTGER1 P34995 1/20 0.35
ALOX15 P16050 1/20 0.34
TSHR P16473 1/20 0.34
ACMSD Q8TDX5 1/20 0.34
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29936118 0.83 KDM1A (0.43) L3MBTL1ALDH1A1KDM4E
SCHEMBL31018412 0.77 L3MBTL1 (0.47) L3MBTL1ALDH1A1KDM4EPLA2G4AACHE
SCHEMBL31018407 0.76 L3MBTL1 (0.44) L3MBTL1ALDH1A1KDM4EPLA2G4AACHE
SCHEMBL1437589 0.75 RAB9A (0.57) L3MBTL1ALDH1A1KDM4EPOLBTSHR
SCHEMBL27174917 0.73 PHGDH (0.38) L3MBTL1ALDH1A1POLB
SCHEMBL1502636 0.73 L3MBTL1 (0.44) L3MBTL1ALDH1A1KDM4EPLA2G4AACHE
SCHEMBL31206497 0.72 HTR2C (0.55)
SCHEMBL23568545 0.71 ALDH1A1 (0.31) ALDH1A1TDP1
SCHEMBL292888 0.71
SCHEMBL31018413 0.71 CA12 (0.44) L3MBTL1ALDH1A1KDM4EPLA2G4AACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240092770-A1 Heterocycle RMB39 Modulators RECURSION PHARMACEUTICALS, INC. 2024-03-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240092770-A1 Heterocycle RMB39 Modulators PRMT9, RCC2, RBBP9 L3MBTL1 135/4885ALDH1A1 3570/4885KDM4E 1141/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.