Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | WDR5 | P61964 | 3/20 | 0.33 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.33 |
| ▸ | BRS3 | P32247 | 2/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.30 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.30 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.30 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23988504 | 0.92 | KMT2A (0.41) | KMT2AHTTMEN1WDR5SARM1 | |
| SCHEMBL23988270 | 0.90 | SARM1 (0.45) | KMT2AWDR5SARM1CYP2C9ALDH1A1 | |
| SCHEMBL24571947 | 0.84 | KMT2A (0.37) | KMT2AHTTMEN1WDR5SARM1 | |
| SCHEMBL23988579 | 0.83 | BRS3 (0.45) | KMT2AHTTMEN1WDR5SARM1 | |
| SCHEMBL23988583 | 0.80 | KMT2A (0.35) | KMT2AHTTWDR5SARM1BRS3 | |
| SCHEMBL24571950 | 0.80 | KMT2A (0.41) | KMT2AHTTMEN1WDR5SARM1 | |
| SCHEMBL23988355 | 0.80 | ATP4A (0.38) | KMT2AHTTMEN1WDR5SARM1 | |
| SCHEMBL23988470 | 0.78 | WDR5 (0.33) | KMT2AHTTWDR5SARM1BRS3 | |
| SCHEMBL23988577 | 0.76 | BRS3 (0.52) | KMT2AHTTMEN1WDR5SARM1 | |
| SCHEMBL23988273 | 0.74 | KMT2A (0.58) | KMT2AHTTMEN1WDR5SARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210338650-A1 | CXCL10 Inhibitors | AFECTA PHARMACEUTICALS, INC. (US) | 2021-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210338650-A1 | CXCL10 Inhibitors | CXCL10, CCL5, CCL11 | KMT2A 3380/4885HTT 3627/4885MEN1 3946/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.