Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | WDR5 | P61964 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | DDAH1 | O94760 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | FASN | P49327 | 2/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SARM1 | Q6SZW1 | 2/20 | 0.41 |
| ▸ | ENGASE | Q8NFI3 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23988420 | 0.89 | CYP2C9 (0.51) | ALDH1A1TP53CYP2C9L3MBTL1NPC1 | |
| SCHEMBL23988520 | 0.86 | CYP2C9 (0.56) | ALDH1A1TP53CYP2C9KMT2ADDAH1 | |
| SCHEMBL23988416 | 0.83 | CYP2C9 (0.42) | ALDH1A1TP53CYP2C9RAB9ADDAH1 | |
| SCHEMBL538298 | 0.81 | ATP4A (0.56) | ALDH1A1CYP2C9WDR5KMT2ADDAH1 | |
| SCHEMBL15475057 | 0.81 | ATP4A (0.66) | ALDH1A1CYP2C9WDR5KMT2ADDAH1 | |
| SCHEMBL23988474 | 0.81 | RUNX1 (0.51) | ALDH1A1CYP2C9DDAH1LMNAMAPT | |
| SCHEMBL30102856 | 0.81 | ATP4A (0.56) | ALDH1A1CYP2C9WDR5KMT2ADDAH1 | |
| SCHEMBL1307379 | 0.80 | KMT2A (0.63) | ALDH1A1TP53CYP2C9L3MBTL1NPC1 | |
| SCHEMBL30905609 | 0.80 | KMT2A (0.63) | ALDH1A1TP53CYP2C9L3MBTL1NPC1 | |
| SCHEMBL6600434 | 0.79 | KMT2A (0.62) | ALDH1A1TP53CYP2C9L3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220202796-A1 | CXCL10 Inhibitors | LAPKO INC, dba AFECTA PHARMACEUTICALS | 2022-06-30 | — | — | US | disclosed |
| US-20210338650-A1 | CXCL10 Inhibitors | AFECTA PHARMACEUTICALS, INC. (US) | 2021-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220202796-A1 | CXCL10 Inhibitors | CXCL10, CCL5, CCL11 | ALDH1A1 3507/4885TP53 1556/4885CYP2C9 4152/4885 |
| US-20210338650-A1 | CXCL10 Inhibitors | CXCL10, CCL5, CCL11 | ALDH1A1 3507/4885TP53 1556/4885CYP2C9 4152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.