Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | WDR5 | P61964 | 3/20 | 0.46 |
| ▸ | ENGASE | Q8NFI3 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | DDAH1 | O94760 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.46 |
| ▸ | NPY1R | P25929 | 2/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23988366 | 0.90 | CYP2C9 (0.47) | CYP2C9NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL23988593 | 0.89 | KMT2A (0.61) | CYP2C9NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL23988433 | 0.89 | CYP2C9 (0.63) | CYP2C9NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL24572357 | 0.82 | ATP4A (0.38) | CYP2C9NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL23988447 | 0.82 | SARM1 (0.47) | NPC1RAB9AKMT2AALDH1A1WDR5 | |
| SCHEMBL23988437 | 0.81 | NPC1 (0.44) | CYP2C9NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL23988466 | 0.77 | ATP4A (0.42) | CYP2C9NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL23988434 | 0.76 | WDR5 (0.57) | CYP2C9NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL23988257 | 0.75 | KMT2A (0.46) | CYP2C9NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL23988421 | 0.74 | CYP2C9 (0.46) | CYP2C9NPC1RAB9ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210338650-A1 | CXCL10 Inhibitors | AFECTA PHARMACEUTICALS, INC. (US) | 2021-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210338650-A1 | CXCL10 Inhibitors | CXCL10, CCL5, CCL11 | CYP2C9 4152/4885NPC1 1955/4885RAB9A 2387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.