Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2400840 | 1.00 | TSHR (0.52) | TSHRL3MBTL1LMNAALDH1A1SLC1A1 | |
| SCHEMBL10676771 | 0.86 | TSHR (0.50) | TSHRL3MBTL1LMNAALDH1A1SLC1A1 | |
| SCHEMBL10682900 | 0.86 | TSHR (0.50) | TSHRL3MBTL1LMNAALDH1A1SLC1A1 | |
| SCHEMBL10676780 | 0.86 | TSHR (0.50) | TSHRL3MBTL1LMNAALDH1A1SLC1A1 | |
| SCHEMBL3601913 | 0.82 | TSHR (0.58) | TSHRL3MBTL1LMNAALDH1A1SLC1A1 | |
| SCHEMBL6138555 | 0.80 | TSHR (0.56) | TSHRL3MBTL1LMNAALDH1A1SLC1A1 | |
| SCHEMBL3573769 | 0.78 | TSHR (0.54) | TSHRL3MBTL1LMNAALDH1A1SLC1A1 | |
| SCHEMBL5844802 | 0.78 | TBXAS1 (0.48) | TSHRLMNAALDH1A1TBXAS1 | |
| SCHEMBL233224 | 0.78 | LTA4H (0.56) | TSHRL3MBTL1LMNAALDH1A1SLC1A1 | |
| SCHEMBL28580826 | 0.78 | PAOX (0.41) | TSHRLMNAALDH1A1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130274470-A1 | Triazolium Carbene Catalysts and Stereoselective Bond Forming Reactions Thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2013-10-17 | — | — | US | disclosed |
| US-20110224431-A1 | Triazolium Carbene Catalysts and Stereoselective Bond Forming Reactions Thereof | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2011-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130274470-A1 | Triazolium Carbene Catalysts and Stereoselective Bond Forming Reactions Thereof | HDHD5, DCX, CLK2 | TSHR 1020/4885L3MBTL1 2227/4885LMNA 4136/4885 |
| US-20110224431-A1 | Triazolium Carbene Catalysts and Stereoselective Bond Forming Reactions Thereof | HDHD5, DCX, CLK2 | TSHR 1020/4885L3MBTL1 2227/4885LMNA 4136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.