Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAM | P19021 | 1/20 | 0.36 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23992172 | 0.81 | HDAC1 (0.47) | PAMPADI4HDAC3HDAC1HDAC2 | |
| SCHEMBL22724123 | 0.77 | RAB9A (0.43) | PADI4KDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL7816689 | 0.76 | GRIK1 (0.49) | PAMALOX5MAOBMAOACYP4F2 | |
| SCHEMBL2760580 | 0.74 | SMYD3 (0.34) | PADI4HTTSMYD3KDM4ENPC1 | |
| SCHEMBL5253130 | 0.74 | ALDH1A1 (0.41) | PADI4ALDH1A1 | |
| SCHEMBL5253126 | 0.74 | ALDH1A1 (0.41) | PADI4ALDH1A1 | |
| SCHEMBL10417759 | 0.71 | GLA (0.50) | PADI4HTTKDM4EALDH1A1RAB9A | |
| SCHEMBL5680262 | 0.71 | PAM (0.70) | PAMHDAC3HDAC1HDAC2HTT | |
| SCHEMBL1124046 | 0.71 | P4HTM (0.55) | PADI4HDAC3HDAC1HDAC2ALOX5 | |
| SCHEMBL1124047 | 0.71 | P4HTM (0.55) | PADI4HDAC3HDAC1HDAC2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021219040-A1 | HISTONE DEACETYLASE INHIBITORS FOR IMMUNOMODULATION IN TUMOR MICROENVIRONMENT | GNT BIOTECH & MEDICALS CORPORATION (CN) | 2021-11-04 | — | — | WO | disclosed |