Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.37 |
| ▸ | PAM | P19021 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12805682 | 0.85 | PAM (0.55) | HDAC1HDAC3HDAC2KDM4EHDAC6 | |
| SCHEMBL12074867 | 0.85 | PAM (0.55) | HDAC1HDAC3HDAC2KDM4EHDAC6 | |
| SCHEMBL17787989 | 0.85 | HDAC1 (0.46) | HDAC1HDAC3HDAC2KDM4EHDAC6 | |
| SCHEMBL2674302 | 0.83 | ADRA2A (0.41) | HDAC1HDAC3HDAC2ADRA2AADRA2B | |
| SCHEMBL23992174 | 0.81 | PAM (0.36) | HDAC1HDAC3HDAC2KDM4EPADI4 | |
| SCHEMBL7816689 | 0.79 | GRIK1 (0.49) | KDM4EPAMPOLBALOX5MAPT | |
| SCHEMBL2760655 | 0.77 | ADRA2A (0.44) | HDAC1HDAC3HDAC2ADRA2AADRA2B | |
| SCHEMBL20152895 | 0.77 | ALDH1A1 (0.46) | HDAC1HDAC3HDAC2ADRA2AADRA2B | |
| SCHEMBL23992178 | 0.77 | TBXAS1 (0.60) | HDAC1HDAC3HDAC2KDM4ETBXAS1 | |
| SCHEMBL10193818 | 0.74 | HDAC1 (0.36) | HDAC1HDAC3HDAC2ADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021219040-A1 | HISTONE DEACETYLASE INHIBITORS FOR IMMUNOMODULATION IN TUMOR MICROENVIRONMENT | GNT BIOTECH & MEDICALS CORPORATION (CN) | 2021-11-04 | — | — | WO | disclosed |