Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | JUN | P05412 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.50 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9488251 | 0.86 | MAPT (0.61) | TBXAS1MAPTRAB9AKDM4ENPC1 | |
| SCHEMBL30227267 | 0.85 | TBXAS1 (0.66) | TBXAS1MAPTRAB9AKDM4ENPC1 | |
| SCHEMBL868080 | 0.85 | TBXAS1 (0.66) | TBXAS1MAPTRAB9AKDM4ENPC1 | |
| SCHEMBL868079 | 0.85 | TBXAS1 (0.66) | TBXAS1MAPTRAB9AKDM4ENPC1 | |
| SCHEMBL17787984 | 0.83 | MAPT (0.62) | TBXAS1MAPTRAB9AKDM4ENPC1 | |
| SCHEMBL3465670 | 0.83 | MAPT (0.51) | TBXAS1MAPTRAB9AKDM4ENPC1 | |
| SCHEMBL4592716 | 0.80 | TBXAS1 (0.59) | TBXAS1MAPTRAB9AKDM4ENPC1 | |
| SCHEMBL10276665 | 0.80 | MAPT (0.53) | TBXAS1MAPTRAB9AKDM4ENPC1 | |
| SCHEMBL30396999 | 0.78 | MAPT (0.51) | TBXAS1MAPTRAB9AKDM4ENPC1 | |
| SCHEMBL4201926 | 0.78 | MAPT (0.51) | TBXAS1MAPTRAB9AKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230263790-A1 | HISTONE DEACETYLASE INHIBITORS FOR IMMUNOMODULATION IN TUMOR MICROENVIRONMENT | Great Novel Therapeutics Biotech & Medicals Corporation (TW) | 2023-08-24 | — | — | US | disclosed |
| US-11672788-B2 | Histone deacetylase inhibitors for immunomodulation in tumor microenvironment | Great Novel Therapeutics Biotech & Medicals Corporation (TW) | 2023-06-13 | — | — | US | disclosed |
| US-20210379032-A1 | HISTONE DEACETYLASE INHIBITORS FOR IMMUNOMODULATION IN TUMOR MICROENVIRONMENT | Great Novel Therapeutics Biotech & Medicals Corporation (TW) | 2021-12-09 | — | — | US | disclosed |
| WO-2021219040-A1 | HISTONE DEACETYLASE INHIBITORS FOR IMMUNOMODULATION IN TUMOR MICROENVIRONMENT | GNT BIOTECH & MEDICALS CORPORATION (CN) | 2021-11-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210379032-A1 | HISTONE DEACETYLASE INHIBITORS FOR IMMUNOMODULATION IN TUMOR MICROENVIRONMENT | HDAC1, HDAC2, HDAC9 | TBXAS1 2522/4885MAPT 3635/4885RAB9A 2886/4885 |
| US-11672788-B2 | Histone deacetylase inhibitors for immunomodulation in tumor microenvironment | HDAC1, HDAC2, HDAC9 | TBXAS1 2522/4885MAPT 3635/4885RAB9A 2886/4885 |
| US-20230263790-A1 | HISTONE DEACETYLASE INHIBITORS FOR IMMUNOMODULATION IN TUMOR MICROENVIRONMENT | HDAC1, HDAC2, HDAC9 | TBXAS1 2522/4885MAPT 3635/4885RAB9A 2886/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.