Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.66 |
| ▸ | PAM | P19021 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | JUN | P05412 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.59 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.56 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.51 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.51 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.51 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30227267 | 1.00 | TBXAS1 (0.66) | TBXAS1PAMMAPTRAB9AKDM4E | |
| SCHEMBL868080 | 1.00 | TBXAS1 (0.66) | TBXAS1PAMMAPTRAB9AKDM4E | |
| SCHEMBL9488251 | 0.88 | MAPT (0.61) | TBXAS1MAPTRAB9AKDM4ENPC1 | |
| SCHEMBL4592716 | 0.87 | TBXAS1 (0.59) | TBXAS1PAMMAPTRAB9AKDM4E | |
| SCHEMBL23992178 | 0.85 | TBXAS1 (0.60) | TBXAS1MAPTRAB9AKDM4ENPC1 | |
| SCHEMBL17787984 | 0.85 | MAPT (0.62) | TBXAS1MAPTRAB9AKDM4ENPC1 | |
| SCHEMBL8828219 | 0.83 | PAM (0.56) | TBXAS1PAMCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL8828225 | 0.83 | PAM (0.56) | TBXAS1PAMCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL1515204 | 0.82 | MAPT (0.53) | TBXAS1PAMMAPTRAB9AKDM4E | |
| SCHEMBL10444608 | 0.81 | TBXAS1 (0.91) | TBXAS1MAPTRAB9AKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4142733-B1 | HISTONE DEACETYLASE INHIBITORS FOR IMMUNOMODULATION IN TUMOR MICROENVIRONMENT | GREAT NOVEL THERAPEUTICS BIOTECH & MEDICALS CORP (TW) | 2025-10-01 | — | — | EP | disclosed |
| US-12213971-B2 | Histone deacetylase inhibitors for immunomodulation in tumor microenvironment | Great Novel Therapeutics Biotech & Medicals Corporation (TW) | 2025-02-04 | — | — | US | disclosed |
| US-20240245099-A1 | AEROSOL-GENERATING ARTICLE WITH BIOMARKER SENSOR | PHILIP MORRIS PRODUCTS S.A. (CH) | 2024-07-25 | — | — | US | disclosed |
| EP-4340648-A1 | AEROSOL-GENERATING ARTICLE WITH BIOMARKER SENSOR | Philip Morris Products S.A. (CH) | 2024-03-27 | — | — | EP | disclosed |
| CN-117295412-A | Aerosol-generating article with biomarker sensor | 菲利普莫里斯生产公司 | 2023-12-26 | — | — | CN | disclosed |
| US-20230263790-A1 | HISTONE DEACETYLASE INHIBITORS FOR IMMUNOMODULATION IN TUMOR MICROENVIRONMENT | Great Novel Therapeutics Biotech & Medicals Corporation (TW) | 2023-08-24 | — | — | US | disclosed |
| US-20230263790-A1 | HISTONE DEACETYLASE INHIBITORS FOR IMMUNOMODULATION IN TUMOR MICROENVIRONMENT | Great Novel Therapeutics Biotech & Medicals Corporation (TW) | 2023-08-24 | — | — | US | disclosed |
| US-20230263790-A1 | HISTONE DEACETYLASE INHIBITORS FOR IMMUNOMODULATION IN TUMOR MICROENVIRONMENT | Great Novel Therapeutics Biotech & Medicals Corporation (TW) | 2023-08-24 | — | — | US | disclosed |
| US-11672788-B2 | Histone deacetylase inhibitors for immunomodulation in tumor microenvironment | Great Novel Therapeutics Biotech & Medicals Corporation (TW) | 2023-06-13 | — | — | US | disclosed |
| US-11672788-B2 | Histone deacetylase inhibitors for immunomodulation in tumor microenvironment | Great Novel Therapeutics Biotech & Medicals Corporation (TW) | 2023-06-13 | — | — | US | disclosed |
| US-20120252810-A1 | FATTY ACID NON-FLUSHING NIACIN DERIVATIVES AND THEIR USES | CATABASIS PHARMACEUTICALS, INC. (US) | 2012-10-04 | — | — | US | disclosed |
| US-20120252810-A1 | FATTY ACID NON-FLUSHING NIACIN DERIVATIVES AND THEIR USES | CATABASIS PHARMACEUTICALS, INC. (US) | 2012-10-04 | — | — | US | disclosed |
| US-20120077808-A1 | Niacin Mimetics, and Methods of Use Thereof | TRUSTEES OF TUFTS COLLEGE (US) | 2012-03-29 | — | — | US | disclosed |
| WO-2011163612-A1 | NIACIN MIMETICS, AND METHODS OF USE THEREOF | TRUSTEES OF TUFTS COLLEGE (US) | 2011-12-29 | — | — | WO | disclosed |
| US-20090312355-A1 | Non-Flushing Niacin Analogues, and Methods of Use Thereof | TRUSTEES OF TUFTS COLLEGE (US) | 2009-12-17 | — | — | US | disclosed |
| US-20090312355-A1 | Non-Flushing Niacin Analogues, and Methods of Use Thereof | TRUSTEES OF TUFTS COLLEGE (US) | 2009-12-17 | — | — | US | disclosed |
| US-20090312355-A1 | Non-Flushing Niacin Analogues, and Methods of Use Thereof | TRUSTEES OF TUFTS COLLEGE (US) | 2009-12-17 | — | — | US | disclosed |
| EP-2054386-A2 | NON-FLUSHING NIACIN ANALOGUES, AND METHODS OF USE THEREOF | TRUSTEES OF TUFTS COLLEGE (US) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008016968-A2 | NON-FLUSHING NIACIN ANALOGUES, AND METHODS OF USE THEREOF | TRUSTEES OF TUFTS COLLEGE (US) | 2008-02-07 | — | — | WO | disclosed |
| WO-2008016968-A2 | NON-FLUSHING NIACIN ANALOGUES, AND METHODS OF USE THEREOF | TRUSTEES OF TUFTS COLLEGE (US) | 2008-02-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120252810-A1 | FATTY ACID NON-FLUSHING NIACIN DERIVATIVES AND THEIR USES | NAMPT, FASN, FFAR2 | TBXAS1 1034/4885PAM 1937/4885MAPT 2701/4885 |
| US-20090312355-A1 | Non-Flushing Niacin Analogues, and Methods of Use Thereof | SLC33A1, CHLSN, APOB | TBXAS1 499/4885PAM 3546/4885MAPT 1937/4885 |
| US-20120077808-A1 | Niacin Mimetics, and Methods of Use Thereof | NAMPT, NADK, NAPRT | TBXAS1 701/4885PAM 450/4885MAPT 3643/4885 |
| US-11672788-B2 | Histone deacetylase inhibitors for immunomodulation in tumor microenvironment | HDAC1, HDAC2, HDAC9 | TBXAS1 2522/4885PAM 3934/4885MAPT 3635/4885 |
| US-20230263790-A1 | HISTONE DEACETYLASE INHIBITORS FOR IMMUNOMODULATION IN TUMOR MICROENVIRONMENT | HDAC1, HDAC2, HDAC9 | TBXAS1 2522/4885PAM 3934/4885MAPT 3635/4885 |
| US-12213971-B2 | Histone deacetylase inhibitors for immunomodulation in tumor microenvironment | HDAC1, HDAC2, HDAC9 | TBXAS1 2522/4885PAM 3934/4885MAPT 3635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.