Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 11/20 | 0.38 |
| ▸ | AR | P10275 | 4/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30164132 | 0.82 | MAOA (0.37) | ARMAOAMAOBHTR2APDK1 | |
| SCHEMBL25005998 | 0.81 | TSHR (0.41) | SLC6A4ARSLC6A2SLC6A3MAOA | |
| SCHEMBL25006008 | 0.78 | TRPV4 (0.46) | SLC6A4ARKCNH2 | |
| SCHEMBL23995539 | 0.75 | AR (0.48) | AR | |
| SCHEMBL23993314 | 0.75 | AR (0.31) | SLC6A4AR | |
| SCHEMBL25004752 | 0.75 | AR (0.31) | SLC6A4AR | |
| SCHEMBL25004524 | 0.75 | SLC6A4 (0.38) | SLC6A4ARHTR2AKCNH2 | |
| SCHEMBL29038963 | 0.74 | MAOA (0.44) | ARMAOAMAOBHTR2A | |
| SCHEMBL16955023 | 0.73 | DRD4 (0.40) | ARMAOAMAOBHTR2A | |
| SCHEMBL25005448 | 0.71 | AR (0.39) | SLC6A4AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222522-A1 | CD73 INHIBITING 2,4-DIOXOPYRIMIDINE COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2021-11-04 | — | — | WO | disclosed |