Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.36 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.36 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.36 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 4/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 5/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.34 |
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.33 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25006008 | 0.86 | TRPV4 (0.46) | SLC6A4ARTRPV4KDM1AKCNH2 | |
| SCHEMBL25005998 | 0.79 | TSHR (0.41) | SLC6A4HTR2AHTR2CHTR2BAR | |
| SCHEMBL20202734 | 0.77 | HTR2A (0.55) | HTR2AHTR2CHTR2BKDM1AKCNH2 | |
| SCHEMBL13192766 | 0.77 | HTR2A (0.55) | HTR2AHTR2CHTR2BKDM1AKCNH2 | |
| SCHEMBL20997590 | 0.77 | HTR2A (0.55) | HTR2AHTR2CHTR2BKDM1AKCNH2 | |
| SCHEMBL808663 | 0.77 | HTR2A (0.55) | HTR2AHTR2CHTR2BKDM1AKCNH2 | |
| SCHEMBL808747 | 0.77 | HTR2A (0.55) | HTR2AHTR2CHTR2BKDM1AKCNH2 | |
| SCHEMBL31734535 | 0.77 | PTP4A3 (0.38) | PGRABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL25005448 | 0.75 | AR (0.39) | SLC6A4PGRARKDM1A | |
| SCHEMBL23993559 | 0.75 | SLC6A4 (0.38) | SLC6A4HTR2AARKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230039553-A1 | CD73 COMPOUNDS | GILEAD SCIENCES, INC. | 2023-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230039553-A1 | CD73 COMPOUNDS | ENTPD5, ENTPD1, NT5E | SLC6A4 1120/4885PGR 1169/4885HTR2A 1593/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.