Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | AGXT | P21549 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL278630 | 0.84 | CASR (0.58) | CASRL3MBTL1ALDH1A1IDO1MEN1 | |
| Hydrochloric Acid SCHEMBL14343449 | 0.82 | CASR (0.57) | CASRL3MBTL1ALDH1A1IDO1MEN1 | |
| SCHEMBL8610978 | 0.81 | ALDH1A1 (0.57) | CASRL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL19289878 | 0.81 | CASR (0.55) | CASRL3MBTL1ALDH1A1IDO1MEN1 | |
| SCHEMBL22342333 | 0.79 | CASR (0.71) | CASRL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL30865858 | 0.79 | CASR (0.54) | CASRL3MBTL1ALDH1A1IDO1MEN1 | |
| SCHEMBL12603587 | 0.79 | CASR (0.71) | CASRL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL19865693 | 0.79 | L3MBTL1 (0.57) | CASRL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL26625761 | 0.79 | L3MBTL1 (0.50) | CASRL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL9781346 | 0.78 | CASR (0.53) | CASRL3MBTL1ALDH1A1IDO1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11168084-B2 | Purine based compounds as toll-like receptor 9 antagonist | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2021-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11168084-B2 | Purine based compounds as toll-like receptor 9 antagonist | TLR9, TLR1, TLR7 | CASR 379/4885L3MBTL1 3833/4885ALDH1A1 2973/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.