Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.51 |
| ▸ | RXRB | P28702 | 2/20 | 0.51 |
| ▸ | RXRG | P48443 | 2/20 | 0.51 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.45 |
| ▸ | TAS2R14 | Q9NYV8 | 10/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM5A | P29375 | 2/20 | 0.41 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10766037 | 0.76 | MEN1 (0.58) | RXRARXRBRXRGTAS2R14MEN1 | |
| SCHEMBL3599505 | 0.74 | HDAC1 (0.59) | RXRARXRBRXRGHDAC3HDAC1 | |
| SCHEMBL19980302 | 0.71 | TSHR (0.37) | MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL26023444 | 0.70 | RXRA (0.58) | RXRARXRBRXRGHDAC3HDAC1 | |
| SCHEMBL16062223 | 0.70 | ACHE (0.64) | TAS2R14MEN1KMT2AALDH1A1 | |
| SCHEMBL5540015 | 0.69 | TSHR (0.43) | MEN1KMT2ALMNAALDH1A1L3MBTL1 | |
| Formic Acid SCHEMBL6820433 | 0.68 | ACHE (0.47) | RXRARXRBRXRGTAS2R14MEN1 | |
| SCHEMBL1116007 | 0.68 | RXRA (0.50) | RXRARXRBRXRGTAS2R14MEN1 | |
| SCHEMBL23189242 | 0.68 | TAAR1 (0.35) | MEN1KMT2AALDH1A1 | |
| SCHEMBL65825 | 0.68 | ALDH1A1 (0.59) | RXRARXRBRXRGTAS2R14MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021226003-A1 | IL4I1 INHIBITORS AND METHODS OF USE | MERCK SHARP & DOHME CORP. (US) | 2021-11-11 | — | — | WO | disclosed |