Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | AOC1 | P19801 | 1/20 | 0.32 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.30 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19848690 | 0.79 | KDM4E (0.36) | ALDH1A1PABPC1TP53AOC1HCAR3 | |
| SCHEMBL5540015 | 0.78 | TSHR (0.43) | TSHRALDH1A1PABPC1TP53MEN1 | |
| SCHEMBL23189242 | 0.76 | TAAR1 (0.35) | TSHRALDH1A1PABPC1MEN1KMT2A | |
| SCHEMBL20344637 | 0.74 | TP53 (0.35) | ALDH1A1TP53HCAR3ALDH3A1ALDH1A3 | |
| SCHEMBL22539189 | 0.72 | ALDH1A1 (0.41) | ALDH1A1TP53LMNA | |
| SCHEMBL23997396 | 0.71 | RXRA (0.51) | ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL33525287 | 0.69 | ALDH1A1 (0.46) | TSHRALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL2243716 | 0.69 | ALDH1A1 (0.46) | TSHRALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL5421931 | 0.69 | TP53 (0.45) | TSHRALDH1A1TP53HCAR3MEN1 | |
| SCHEMBL30527294 | 0.69 | ALDH1A1 (0.57) | TSHRALDH1A1PABPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2956452-B1 | HETEROCYCLIC AMIDES AS KINASE INHIBITORS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2018-03-21 | — | — | EP | disclosed |