Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | ANPEP | P15144 | 2/20 | 0.36 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.36 |
| ▸ | CASR | P41180 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8932490 | 0.77 | EPHX1 (0.44) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| SCHEMBL24106692 | 0.77 | IDO1 (0.46) | DPP4DPP7ALDH1A1TP53CYP3A4 | |
| SCHEMBL24106695 | 0.77 | IDO1 (0.46) | DPP4DPP7ALDH1A1TP53CYP3A4 | |
| SCHEMBL5018923 | 0.75 | IDO1 (0.46) | DPP4DPP7ALDH1A1TP53CYP3A4 | |
| SCHEMBL23997487 | 0.73 | DPP4 (0.44) | DPP4DPP7ALDH1A1TP53IDO1 | |
| SCHEMBL7766820 | 0.73 | ALDH1A1 (0.46) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| SCHEMBL20287965 | 0.72 | ALDH1A1 (0.44) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| SCHEMBL21063311 | 0.71 | ALDH1A1 (0.41) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| SCHEMBL23997631 | 0.71 | SAE1 (0.46) | DPP4DPP7IDO1GAAPPARG | |
| SCHEMBL24106651 | 0.70 | DPP4 (0.47) | DPP4DPP7ALDH1A1TP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230174562-A1 | RADIO-AND CHEMO-PROTECTIVE COMPOUNDS | Tonix Pharmaceuticals, Inc. | 2023-06-08 | — | — | US | disclosed |
| US-20230174562-A1 | RADIO-AND CHEMO-PROTECTIVE COMPOUNDS | Tonix Pharmaceuticals, Inc. | 2023-06-08 | — | — | US | disclosed |
| US-20230138150-A1 | RADIO-PROTECTIVE AND CHEMO-PROTECTIVE SUBSTITUTED THIOLS | Tonix Pharmaceuticals, Inc. | 2023-05-04 | — | — | US | disclosed |
| US-20230138150-A1 | RADIO-PROTECTIVE AND CHEMO-PROTECTIVE SUBSTITUTED THIOLS | Tonix Pharmaceuticals, Inc. | 2023-05-04 | — | — | US | disclosed |
| US-11566032-B2 | Radio-protective and chemo-protective substituted thiols | Tonix Pharmaceuticals, Inc. (US) | 2023-01-31 | — | — | US | disclosed |
| US-20210388011-A1 | RADIO-AND CHEMO-PROTECTIVE COMPOUNDS | TONIX PHARMACEUTICALS HOLDING CORP. | 2021-12-16 | — | — | US | disclosed |
| WO-2021226559-A1 | RADIO-AND CHEMO-PROTECTIVE COMPOUNDS | Tonix Pharmaceuticals, Inc. (US) | 2021-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230174562-A1 | RADIO-AND CHEMO-PROTECTIVE COMPOUNDS | MGMT, RCOR3, TSPO | DPP4 2414/4885DPP7 2596/4885ALDH1A1 926/4885 |
| US-20210388011-A1 | RADIO-AND CHEMO-PROTECTIVE COMPOUNDS | MGMT, GSTP1, GSTA1 | DPP4 894/4885DPP7 1008/4885ALDH1A1 152/4885 |
| US-11566032-B2 | Radio-protective and chemo-protective substituted thiols | MGMT, GSTP1, GSTA1 | DPP4 757/4885DPP7 853/4885ALDH1A1 239/4885 |
| US-20230138150-A1 | RADIO-PROTECTIVE AND CHEMO-PROTECTIVE SUBSTITUTED THIOLS | MGMT, GSTA1, GSTP1 | DPP4 1408/4885DPP7 1460/4885ALDH1A1 93/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.