⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31444312 | 0.78 | TAAR1 (0.36) | — | |
| SCHEMBL29246605 | 0.72 | PRCP (0.35) | — | |
| SCHEMBL29748355 | 0.72 | PRCP (0.35) | — | |
| SCHEMBL24005410 | 0.72 | PRCP (0.35) | — | |
| SCHEMBL30421244 | 0.72 | PRCP (0.35) | — | |
| SCHEMBL25478453 | 0.71 | PRCP (0.31) | — | |
| SCHEMBL25478405 | 0.70 | HTR7 (0.33) | — | |
| SCHEMBL25478249 | 0.69 | — | — | |
| SCHEMBL24005501 | 0.69 | GABRA1 (0.32) | — | |
| SCHEMBL25613625 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021223736-A1 | COMPOUNDS AS BCL-2 INHIBITORS | FOCHON PHARMACEUTICALS, LTD. (CN) | 2021-11-11 | — | — | WO | disclosed |