⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25478405 | 0.85 | HTR7 (0.33) | — | |
| SCHEMBL25492802 | 0.82 | — | — | |
| SCHEMBL25613625 | 0.82 | — | — | |
| SCHEMBL25478279 | 0.74 | ADRB2 (0.36) | — | |
| SCHEMBL25478281 | 0.73 | NSD2 (0.34) | — | |
| SCHEMBL25478404 | 0.72 | NR3C2 (0.32) | — | |
| SCHEMBL25478218 | 0.71 | OPRM1 (0.32) | — | |
| SCHEMBL25478451 | 0.70 | NSD2 (0.35) | — | |
| SCHEMBL24005488 | 0.69 | — | — | |
| SCHEMBL6276897 | 0.67 | TSHR (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023088167-A1 | COMPOUNDS AS BCL-2 INHIBITORS | FOCHON PHARMACEUTICALS, LTD. (CN) | 2023-05-25 | — | — | WO | disclosed |