Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2400679 | 1.00 | HTR2C (0.36) | HTR2CP2RY6TMEM97DRD2HTR2A | |
| SCHEMBL2399979 | 1.00 | HTR2C (0.36) | HTR2CP2RY6TMEM97DRD2HTR2A | |
| SCHEMBL1922162 | 1.00 | HTR2C (0.36) | HTR2CP2RY6TMEM97DRD2HTR2A | |
| SCHEMBL1923837 | 1.00 | HTR2C (0.36) | HTR2CP2RY6TMEM97DRD2HTR2A | |
| SCHEMBL8170741 | 0.81 | HTR2C (0.33) | HTR2CDRD2HTR2A | |
| SCHEMBL15372185 | 0.81 | HTR2C (0.33) | HTR2CDRD2HTR2A | |
| SCHEMBL12847217 | 0.81 | HTR2C (0.33) | HTR2CDRD2HTR2A | |
| SCHEMBL10441576 | 0.81 | HTR2C (0.33) | HTR2CDRD2HTR2A | |
| SCHEMBL2257173 | 0.81 | HTR2C (0.33) | HTR2CDRD2HTR2A | |
| SCHEMBL1735849 | 0.76 | ABCG2 (0.32) | HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8981127-B2 | Method for preparing nebivolol | ZACH SYSTEM (FR) | 2015-03-17 | — | — | US | disclosed |
| EP-2328883-B1 | METHOD FOR PREPARING NEBIVOLOL | ZACH SYSTEM (FR) | 2014-08-06 | — | — | EP | disclosed |
| US-20110237808-A1 | METHOD FOR PREPARING NEBIVOLOL | ZACH SYSTEM (FR) | 2011-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110237808-A1 | METHOD FOR PREPARING NEBIVOLOL | ADRB1, ADRA1B, ADRB2 | HTR2C 1494/4885P2RY6 3776/4885TMEM97 1656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.