Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | CXCR1 | P25024 | 3/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1148 | 0.89 | TSHR (0.61) | TSHRTP53IDO1L3MBTL1TYR | |
| SCHEMBL29487262 | 0.89 | TSHR (0.61) | TSHRTP53IDO1L3MBTL1TYR | |
| SCHEMBL2399751 | 0.86 | TSHR (0.54) | TSHRTP53CXCR1CXCR2ALDH1A1 | |
| SCHEMBL8343428 | 0.84 | TSHR (0.49) | TSHRTP53IDO1L3MBTL1TYR | |
| P-Cymene SCHEMBL23296191 | 0.83 | TP53 (0.54) | TSHRTP53IDO1TYRACACB | |
| 2-Methylpentanal SCHEMBL4778956 | 0.80 | TSHR (0.51) | TSHRTP53IDO1L3MBTL1TYR | |
| SCHEMBL23212331 | 0.79 | TSHR (0.58) | TSHRTP53CXCR1CXCR2PTGS1 | |
| SCHEMBL16268509 | 0.78 | TP53 (0.49) | TSHRTP53IDO1TYRACACB | |
| SCHEMBL112939 | 0.75 | TSHR (0.58) | TSHRTP53CXCR1CXCR2FAAH | |
| SCHEMBL11479345 | 0.75 | TSHR (0.58) | TSHRTP53CXCR1CXCR2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110217257-A1 | NOVEL 4-ALKYL CYCLOHEXANEPROPANAL COMPOUNDS AND THEIR USE IN PERFUME COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2011-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110217257-A1 | NOVEL 4-ALKYL CYCLOHEXANEPROPANAL COMPOUNDS AND THEIR USE IN PERFUME COMPOSITIONS | TRPA1, FAAH2, FAAH | TSHR 4860/4885TP53 2980/4885IDO1 2640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.