Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14734035 | 0.84 | DRD2 (0.45) | DRD2SIGMAR1SLC6A4SMN1; SMN2DRD3 | |
| SCHEMBL24009185 | 0.84 | SMN1; SMN2 (0.42) | SMN1; SMN2 | |
| SCHEMBL24837374 | 0.80 | GPR119 (0.37) | DRD2SMN1; SMN2DRD3 | |
| SCHEMBL20609803 | 0.78 | DRD2 (0.41) | DRD2SIGMAR1SLC6A4SMN1; SMN2 | |
| SCHEMBL19544965 | 0.77 | NCF1 (0.34) | — | |
| SCHEMBL806006 | 0.77 | DRD2 (0.40) | DRD2SIGMAR1SMN1; SMN2DRD3 | |
| SCHEMBL26400721 | 0.77 | CYP2D6 (0.46) | SMN1; SMN2 | |
| SCHEMBL29251912 | 0.73 | HTT (0.50) | DRD2SIGMAR1SMN1; SMN2 | |
| SCHEMBL5471689 | 0.72 | DRD2 (0.48) | DRD2SLC6A4SMN1; SMN2 | |
| SCHEMBL12678541 | 0.72 | DRD2 (0.42) | DRD2SIGMAR1PABPC1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021225969-A1 | IMINO SULFANONE INHIBITORS OF ENPP1 | VOLASTRA THERAPEUTICS, INC. (US) | 2021-11-11 | — | — | WO | disclosed |