Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21806200 | 0.86 | CA12 (0.43) | MAOBALDH1A1RAB9ASMN1; SMN2CA12 | |
| SCHEMBL21806248 | 0.81 | CA12 (0.40) | MAOBALDH1A1CA12CA9KDM4E | |
| SCHEMBL24012442 | 0.79 | HPGD (0.61) | ALDH1A1RAB9ASMN1; SMN2HDAC1TP53 | |
| SCHEMBL21806302 | 0.74 | MAOB (0.52) | MAOBALDH1A1CA12MAOAAKR1B10 | |
| SCHEMBL21806139 | 0.72 | MAOB (0.48) | MAOBALDH1A1KDM4EMAOAAKR1B10 | |
| SCHEMBL21806222 | 0.72 | ALDH1A1 (0.48) | MAOBALDH1A1KDM4EMAOAAKR1B10 | |
| SCHEMBL25707896 | 0.71 | ALDH1A1 (0.64) | MAOBALDH1A1RAB9ASMN1; SMN2CA12 | |
| Trifluoroacetic Acid SCHEMBL21806084 | 0.71 | MAOB (0.48) | MAOBALDH1A1CA12MAOAAKR1B10 | |
| SCHEMBL24176809 | 0.70 | ALDH1A1 (0.81) | MAOBALDH1A1RAB9ASMN1; SMN2CA12 | |
| SCHEMBL21806086 | 0.70 | CDYL (0.42) | ALDH1A1RAB9ASMN1; SMN2KDM4EHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210349101-A1 | COUMARIN-BASED CROSSLINKING REAGENTS | VENTANA MEDICAL SYSTEMS, INC. | 2021-11-11 | — | — | US | disclosed |