Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 3/20 | 0.38 |
| ▸ | NCF1 | P14598 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 3/20 | 0.35 |
| ▸ | ACHE | P22303 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21806200 | 0.89 | CA12 (0.43) | CA12CA9DRD3NCF1MAOB | |
| SCHEMBL24012367 | 0.84 | MAOB (0.38) | CA12MAOBCA1CA2CA4 | |
| SCHEMBL24012369 | 0.81 | MAOB (0.45) | CA12NCF1MAOBCA1CA2 | |
| SCHEMBL24012380 | 0.81 | MAOB (0.50) | CA12CA9MAOBKDM4EALDH1A1 | |
| SCHEMBL13056381 | 0.81 | ADORA3 (0.43) | CA12CA9DRD3DRD2KDM4E | |
| SCHEMBL24012362 | 0.81 | ALDH1A1 (0.35) | CA12MAOBCA1CA2CA4 | |
| SCHEMBL13248221 | 0.80 | ADORA3 (0.44) | CA12CA9DRD3DRD2KDM4E | |
| SCHEMBL24012368 | 0.78 | KMT2A (0.45) | CA12DRD3NCF1MAOBCA1 | |
| SCHEMBL21806658 | 0.77 | MAOB (0.33) | CA12MAOBCA1CA2CA4 | |
| SCHEMBL24012364 | 0.75 | PSMB8 (0.35) | DRD3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210349101-A1 | COUMARIN-BASED CROSSLINKING REAGENTS | VENTANA MEDICAL SYSTEMS, INC. | 2021-11-11 | — | — | US | disclosed |
| EP-3853214-A1 | COUMARIN-BASED CROSSLINKING REAGENTS | Ventana Medical Systems, Inc. (US) | 2021-07-28 | — | — | EP | disclosed |
| WO-2020058339-A1 | COUMARIN-BASED CROSSLINKING REAGENTS | VENTANA MEDICAL SYSTEMS, INC. (US) | 2020-03-26 | — | — | WO | disclosed |