Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | CPT2 | P23786 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30686973 | 0.90 | HMGCR (0.42) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 | |
| SCHEMBL22777794 | 0.78 | HMGCR (0.40) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 | |
| SCHEMBL17849328 | 0.78 | HMGCR (0.40) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 | |
| SCHEMBL28373015 | 0.77 | GAA (0.46) | ALDH1A1CYP1A2 | |
| SCHEMBL1670466 | 0.76 | HMGCR (0.39) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 | |
| SCHEMBL11251970 | 0.76 | — | — | |
| SCHEMBL5634001 | 0.75 | HMGCR (0.42) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 | |
| SCHEMBL24754736 | 0.73 | HMGCR (0.46) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 | |
| SCHEMBL3654996 | 0.73 | HMGCR (0.46) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 | |
| SCHEMBL9141654 | 0.73 | ALDH1A1 (0.46) | CYP2C19HIF1ATSHRALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12435071-B2 | Bryostatin compounds and methods of preparing the same | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2025-10-07 | — | — | US | disclosed |
| WO-2025133657-A1 | BIARYL-TYPE HETEROCYCLIC COMPOUNDS AND ANTI-BACTERIAL USES THEREOF | DEBRECENI EGYETEM (HU) | 2025-06-26 | — | — | WO | disclosed |
| US-20240116908-A1 | BRYOSTATIN COMPOUNDS AND METHODS OF PREPARING THE SAME | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2024-04-11 | — | — | US | disclosed |
| US-11746105-B2 | Bryostatin compounds and methods of preparing the same | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2023-09-05 | — | — | US | disclosed |
| US-20210292309-A1 | BRYOSTATIN COMPOUNDS AND METHODS OF PREPARING THE SAME | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2021-09-23 | — | — | US | disclosed |
| US-10947221-B2 | Bryostatin compounds and methods of preparing the same | THE BOARD OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2021-03-16 | — | — | US | disclosed |
| US-20190292172-A1 | BRYOSTATIN COMPOUNDS AND METHODS OF PREPARING THE SAME | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2019-09-26 | — | — | US | disclosed |
| EP-3523296-A1 | BRYOSTATIN COMPOUNDS AND METHODS OF PREPARING THE SAME | The Board of Trustees of the Leland Stanford Junior University (US) | 2019-08-14 | — | — | EP | disclosed |
| CN-109923110-A | Bryostatin compound and preparation method | 小利兰·斯坦福大学托管委员会 | 2019-06-21 | — | — | CN | disclosed |
| WO-2018067382-A1 | BRYOSTATIN COMPOUNDS AND METHODS OF PREPARING THE SAME | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2018-04-12 | — | — | WO | disclosed |
| WO-2007107470-A2 | PYRAZOLES AS 11-BETA-HSD-1 | F. HOFFMANN-LA ROCHE AG (CH) | 2007-09-27 | — | — | WO | disclosed |
| EP-1458703-B1 | ISOCHROMAN COMPOUNDS FOR TREATMENT OF CNS DISORDERS | LILLY CO ELI (US) | 2007-02-28 | — | — | EP | disclosed |
| EP-1639121-A2 | SYNTHESIS OF BETA -L-2-DEOXY NUCLEOSIDES | Idenix (Cayman) Limited (KY) | 2006-03-29 | — | — | EP | disclosed |
| US-20050059632-A1 | Synthesis of beta-L-2'-deoxy nucleosides | NOVARTIS AG (CH) | 2005-03-17 | — | — | US | disclosed |
| US-20050014750-A1 | Isochroman compounds for treatment of cns disorders | ELI LILLY AND COMPANY | 2005-01-20 | — | — | US | disclosed |
| WO-2005003374-A2 | SYNTHESIS OF β-L-2-DEOXY NUCLEOSIDES | IDENIX (CAYMAN) LIMITED (KY) | 2005-01-13 | — | — | WO | disclosed |
| EP-1458703-A1 | ISOCHROMAN COMPOUNDS FOR TREATMENT OF CNS DISORDERS | ELI LILLY AND COMPANY (US) | 2004-09-22 | — | — | EP | disclosed |
| WO-2003053948-A1 | ISOCHROMAN COMPOUNDS FOR TREATMENT OF CNS DISORDERS | ELI LILLY AND COMPANY (US) | 2003-07-03 | — | — | WO | disclosed |
| US-6452042-B1 | ELIMINATION OF AN ALCOHOL FROM A SUBSTITUTED MALONDIALDEHYDE ACETAL; THERMALLY STABLE, MORE REACTIVE CHEMICAL INTERMEDIATES FOR SUCH AS SYNTHESIS OF HETEROCYCLES | CREANOVA, INC. | 2002-09-17 | — | — | US | disclosed |
| US-4634773-A | Thiazolidinylethylchlorocarbonates | POLAROID CORPORATION (US) | 1987-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11746105-B2 | Bryostatin compounds and methods of preparing the same | PROKR1, PBK, PROKR2 | HMGCR 1491/4885CHRM1 4447/4885TBXA2R 629/4885 |
| US-10947221-B2 | Bryostatin compounds and methods of preparing the same | PROKR1, PBK, PROKR2 | HMGCR 1491/4885CHRM1 4447/4885TBXA2R 629/4885 |
| US-20050014750-A1 | Isochroman compounds for treatment of cns disorders | INA, CNR2, CNR1 | HMGCR 690/4885CHRM1 26/4885TBXA2R 1927/4885 |
| US-20210292309-A1 | BRYOSTATIN COMPOUNDS AND METHODS OF PREPARING THE SAME | PROKR1, PBK, PROKR2 | HMGCR 1491/4885CHRM1 4447/4885TBXA2R 629/4885 |
| US-20190292172-A1 | BRYOSTATIN COMPOUNDS AND METHODS OF PREPARING THE SAME | PROKR1, PBK, PROKR2 | HMGCR 1491/4885CHRM1 4447/4885TBXA2R 629/4885 |
| US-20240116908-A1 | BRYOSTATIN COMPOUNDS AND METHODS OF PREPARING THE SAME | PROKR1, PBK, PROKR2 | HMGCR 1491/4885CHRM1 4447/4885TBXA2R 629/4885 |
| US-20050059632-A1 | Synthesis of beta-L-2'-deoxy nucleosides | DUT, DERA, RNASEL | HMGCR 2182/4885CHRM1 4076/4885TBXA2R 3411/4885 |
| US-12435071-B2 | Bryostatin compounds and methods of preparing the same | PROKR1, PBK, PROKR2 | HMGCR 1491/4885CHRM1 4447/4885TBXA2R 629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.