Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.37 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 2/20 | 0.34 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MPI | P34949 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19667840 | 0.87 | GABRA1 (0.39) | HTR2BPDE2AHTR2CCYP3A4KDM4E | |
| SCHEMBL12463310 | 0.83 | HTR2B (0.42) | SIGMAR1HTR1BHTR2BGPR65SLC6A4 | |
| SCHEMBL25688660 | 0.79 | HTR1B (0.37) | SIGMAR1HTR1BHTR2BGPR65F2RL1 | |
| SCHEMBL1253164 | 0.79 | PDE2A (0.43) | SIGMAR1HTR1BHTR2BGPR65PDE2A | |
| SCHEMBL27467123 | 0.79 | HTR1B (0.37) | SIGMAR1HTR1BHTR2BGPR65F2RL1 | |
| SCHEMBL7003988 | 0.79 | PDE2A (0.43) | SIGMAR1HTR1BHTR2BGPR65PDE2A | |
| SCHEMBL27833885 | 0.79 | CNR1 (0.38) | HTR1BHTR2BGPR65CXCR5HTR2C | |
| SCHEMBL14065417 | 0.78 | CES2 (0.37) | SIGMAR1HTR1BHTR2BGPR65F2RL1 | |
| Hydrochloric Acid SCHEMBL2149832 | 0.78 | PDE2A (0.42) | SIGMAR1HTR1BHTR2BGPR65PDE2A | |
| SCHEMBL19667842 | 0.77 | CYP1A2 (0.46) | HTR2BHTR2CCYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11174282-B2 | Aminosteroid derivatives and process for producing same | UNIVERSITé LAVAL (CA) | 2021-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11174282-B2 | Aminosteroid derivatives and process for producing same | HSD17B11, HSD17B7, CYP19A1 | SIGMAR1 1322/4885HTR1B 1715/4885HTR2B 1874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.