Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24660083 | 0.82 | HTT (0.31) | HTT | |
| SCHEMBL26553988 | 0.82 | HTT (0.31) | HTT | |
| SCHEMBL10037291 | 0.78 | LMNA (0.44) | HTT | |
| SCHEMBL1592788 | 0.78 | LMNA (0.44) | HTT | |
| SCHEMBL5429806 | 0.78 | LMNA (0.44) | HTT | |
| SCHEMBL19483337 | 0.77 | ALDH1A1 (0.38) | HTT | |
| SCHEMBL15119980 | 0.77 | ALDH1A1 (0.38) | HTT | |
| SCHEMBL17403511 | 0.76 | LMNA (0.34) | HTT | |
| SCHEMBL16017678 | 0.74 | FKBP1A (0.36) | HTT | |
| SCHEMBL4901400 | 0.73 | EPHX1 (0.35) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11174282-B2 | Aminosteroid derivatives and process for producing same | UNIVERSITé LAVAL (CA) | 2021-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11174282-B2 | Aminosteroid derivatives and process for producing same | HSD17B11, HSD17B7, CYP19A1 | HTT 4804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.