Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 3/20 | 0.48 |
| ▸ | FEN1 | P39748 | 3/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
| ▸ | PI4KA | P42356 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 4/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18812089 | 0.84 | ALOX5AP (0.43) | ALOX5APFEN1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL21044461 | 0.81 | ALOX5AP (0.49) | ALOX5APFEN1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL21044391 | 0.80 | ALOX5AP (0.51) | ALOX5APFEN1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL18518453 | 0.77 | ALDH1A1 (0.48) | ALOX5APFEN1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL16640379 | 0.77 | ALOX5AP (0.48) | ALOX5APFEN1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL20456783 | 0.77 | ALOX5AP (0.39) | ALOX5APFEN1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL20469167 | 0.73 | ASIC3 (0.40) | ALOX5APFEN1MAPTBACE1 | |
| SCHEMBL22053021 | 0.73 | ALOX5AP (0.45) | ALOX5APFEN1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL2559473 | 0.73 | KMO (0.49) | ALOX5APFEN1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL22334571 | 0.72 | PIK3CD (0.45) | ALOX5APFEN1PIK3CDPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3909949-A1 | ATAZANAVIR (ATV) ANALOGUES FOR TREATING HIV INFECTIONS | Gilead Sciences, Inc. (US) | 2021-11-17 | — | — | EP | disclosed |