Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2078143 | 1.00 | KMT2A (0.64) | KMT2AALDH1A1MEN1PTGS1PTGS2 | |
| SCHEMBL7096973 | 0.83 | KMT2A (0.55) | KMT2AALDH1A1MEN1PTGS1PTGS2 | |
| SCHEMBL7279830 | 0.83 | KMT2A (0.47) | KMT2ALMNA | |
| SCHEMBL11861772 | 0.82 | KEAP1 (0.45) | KMT2AALDH1A1MEN1LMNAKEAP1 | |
| SCHEMBL27441057 | 0.82 | ESR1 (0.54) | KMT2A | |
| SCHEMBL10967855 | 0.80 | KMT2A (0.50) | KMT2AALDH1A1GAATSHRKEAP1 | |
| SCHEMBL20943223 | 0.80 | CYP1A2 (0.48) | KMT2AALDH1A1TSHR | |
| SCHEMBL2400228 | 0.80 | MMP8 (0.56) | KMT2AMEN1GAALMNATSHR | |
| SCHEMBL324209 | 0.80 | MMP8 (0.56) | KMT2AMEN1GAALMNATSHR | |
| SCHEMBL4290959 | 0.80 | MMP8 (0.56) | KMT2AMEN1GAALMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8252559-B2 | Methods and systems for selective fluorination of organic molecules | THE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2012-08-28 | — | — | US | disclosed |
| US-8252559-B2 | Methods and systems for selective fluorination of organic molecules | THE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2012-08-28 | — | — | US | disclosed |
| US-8252559-B2 | Methods and systems for selective fluorination of organic molecules | THE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2012-08-28 | — | — | US | disclosed |
| US-8026085-B2 | Methods and systems for selective fluorination of organic molecules | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2011-09-27 | — | — | US | disclosed |
| US-8026085-B2 | Methods and systems for selective fluorination of organic molecules | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2011-09-27 | — | — | US | disclosed |
| US-20090209010-A1 | METHODS AND SYSTEMS FOR SELECTIVE FLUORINATION OF ORGANIC MOLECULES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2009-08-20 | — | — | US | disclosed |
| US-20090209010-A1 | METHODS AND SYSTEMS FOR SELECTIVE FLUORINATION OF ORGANIC MOLECULES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2009-08-20 | — | — | US | disclosed |
| US-20090209010-A1 | METHODS AND SYSTEMS FOR SELECTIVE FLUORINATION OF ORGANIC MOLECULES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2009-08-20 | — | — | US | disclosed |
| US-20090061471-A1 | Methods and systems for selective fluorination of organic molecules | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2009-03-05 | — | — | US | disclosed |
| US-20090061471-A1 | Methods and systems for selective fluorination of organic molecules | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2009-03-05 | — | — | US | disclosed |
| WO-2009018116-A1 | PROCESS FOR FLUORINATION USING 1,1,2,2-TETRAFLUOROETHYL-N,N-DIMETHYLAMINE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-02-05 | — | — | WO | disclosed |
| WO-2009018116-A1 | PROCESS FOR FLUORINATION USING 1,1,2,2-TETRAFLUOROETHYL-N,N-DIMETHYLAMINE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-02-05 | — | — | WO | disclosed |
| US-20090030246-A1 | PROCESS FOR FLUORINATION USING 1,1,2,2-TETRAFLUOROETHYL-N,N-DIMETHYLAMINE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-01-29 | — | — | US | disclosed |
| US-20090030246-A1 | PROCESS FOR FLUORINATION USING 1,1,2,2-TETRAFLUOROETHYL-N,N-DIMETHYLAMINE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-01-29 | — | — | US | disclosed |
| US-20090030246-A1 | PROCESS FOR FLUORINATION USING 1,1,2,2-TETRAFLUOROETHYL-N,N-DIMETHYLAMINE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090030246-A1 | PROCESS FOR FLUORINATION USING 1,1,2,2-TETRAFLUOROETHYL-N,N-DIMETHYLAMINE | FLNA, FLNB, AFF1 | KMT2A 980/4885ALDH1A1 451/4885MEN1 458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.