Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KLK7 | P49862 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7096527 | 0.85 | TSHR (0.41) | KMT2APOLBALDH1A1KEAP1NFE2L2 | |
| SCHEMBL2401919 | 0.83 | KMT2A (0.64) | KMT2APTGS1PTGS2MEN1ALDH1A1 | |
| SCHEMBL2078143 | 0.83 | KMT2A (0.64) | KMT2APTGS1PTGS2MEN1ALDH1A1 | |
| SCHEMBL7096258 | 0.83 | MMP8 (0.49) | KMT2AMEN1LMNATSHRGAA | |
| SCHEMBL7100984 | 0.82 | ALDH1A1 (0.47) | KMT2APTGS1PTGS2POLBALDH1A1 | |
| SCHEMBL7101644 | 0.81 | LMNA (0.46) | KMT2AALDH1A1LMNATSHRMAPT | |
| SCHEMBL28273233 | 0.79 | KMT2A (0.58) | KMT2APTGS1PTGS2MEN1ALDH1A1 | |
| SCHEMBL7101022 | 0.79 | TSHR (0.46) | POLBALDH1A1LMNATSHRL3MBTL1 | |
| SCHEMBL27708803 | 0.78 | KMT2A (0.53) | KMT2APTGS1PTGS2MEN1ALDH1A1 | |
| SCHEMBL13379411 | 0.77 | KEAP1 (0.44) | KMT2APOLBALDH1A1LMNAKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1038861-B1 | 4-FLUORO-3-OXOCARBOXYLIC ESTERS AND PROCESS FOR PRODUCING THE SAME | UBE INDUSTRIES (JP) | 2003-09-03 | — | — | EP | disclosed |
| US-6593488-B1 | Reacting 2-fluorocarboxylate with carboxylate | UBE INDUSTRIES, LTD. (JP) | 2003-07-15 | — | — | US | disclosed |
| EP-1038861-A1 | 4-FLUORO-3-OXOCARBOXYLIC ESTERS AND PROCESS FOR PRODUCING THE SAME | UBE INDUSTRIES LIMITED (JP) | 2000-09-27 | — | — | EP | disclosed |