SCHEMBL2402174

SCHEMBL2402174

O=C(O)/C(=C(\C(=O)O)C(C(F)(F)F)C(F)(F)F)C(C(F)(F)F)C(F)(F)F

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
THRB P10828 1/20 0.30
RECQL P46063 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4346106 1.00 ALDH1A1 (0.30) ALDH1A1THRBRECQL
SCHEMBL9064018 1.00 ALDH1A1 (0.30) ALDH1A1THRBRECQL
SCHEMBL3514874 0.87
SCHEMBL23733014 0.75
SCHEMBL568947 0.73 ALDH1A1 (0.33) ALDH1A1THRBRECQL
Hydrochloric Acid SCHEMBL9770255 0.71 LMNA (0.32) ALDH1A1THRBRECQL
SCHEMBL723672 0.71 TET2 (0.32)
SCHEMBL891709 0.69
SCHEMBL23733172 0.69
SCHEMBL431487 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090197167-A1 Fluorinated Additives For Lithium Ion Batteries SOLVAY FLUOR GMBH (DE) 2009-08-06 US claimed
US-20030194378-A1 Novel aerosol formulation containing a polar fluorinated molecule ASTRAZENECA AB (SE) 2003-10-16 US claimed
EP-1303258-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE AstraZeneca AB (SE) 2003-04-23 EP claimed
WO-2002003958-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE ASTRAZENECA AB (SE) 2002-01-17 WO claimed
US-9825331-B2 Fluorinated derivatives of meldrum's acid, a method for the preparation of the same, and their use as a solvent additive SOLVAY SA (BE) 2017-11-21 US disclosed
US-20140322618-A1 FLUORINATED DERIVATIVES OF MELDRUM'S ACID, A METHOD FOR THE PREPARATION OF THE SAME, AND THEIR USE AS A SOLVENT ADDITIVE SOLVAY SA (BE) 2014-10-30 US disclosed
US-20140045078-A1 LITHIUM AIR BATTERY CELL SOLVAY SA (BE) 2014-02-13 US disclosed
US-8012658-B2 binder resin including a polyester resin and a vinyl resin which the monomer having an alkyloxysilyl group, a wax and a colors; good fixability, durability, noncracking during high speed recording without causing the offset problem RICOH COMPANY LIMITED (JP) 2011-09-06 US disclosed
US-7829254-B2 Non-magnetic toner, image forming apparatus and process cartridge RICOH COMPANY, LTD. (JP) 2010-11-09 US disclosed
US-20090197167-A1 Fluorinated Additives For Lithium Ion Batteries SOLVAY FLUOR GMBH (DE) 2009-08-06 US disclosed
US-20080220357-A1 TONER FOR DEVELOPING ELECTROSTATIC IMAGE, AND IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING THE TONER RICOH COMPANY LIMITED (JP) 2008-09-11 US disclosed
US-20070218388-A1 NON-MAGNETIC TONER, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2007-09-20 US disclosed
EP-1303258-B1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE ASTRAZENECA AB (SE) 2006-10-11 EP disclosed
US-20030194378-A1 Novel aerosol formulation containing a polar fluorinated molecule ASTRAZENECA AB (SE) 2003-10-16 US disclosed
US-20030162853-A1 Use of adsorbent polymer particles in DNA separation PROMETIC BIOSCIENCES LTD. (GB) 2003-08-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140322618-A1 FLUORINATED DERIVATIVES OF MELDRUM'S ACID, A METHOD FOR THE PREPARATION OF THE SAME, AND THEIR USE AS A SOLVENT ADDITIVE FXR2, FXR1, SLC10A1 ALDH1A1 1252/4885THRB 3934/4885RECQL 2609/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.