SCHEMBL849875

SCHEMBL849875

CC(=O)Nc1cc(C)cc(C)c1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.77
KMT2A Q03164 1/20 0.77
HSD17B10 Q99714 2/20 0.63
LMNA P02545 2/20 0.60
TDP1 Q9NUW8 2/20 0.60
NPSR1 Q6W5P4 2/20 0.53
HTT P42858 2/20 0.53
THRB P10828 1/20 0.53
GAA P10253 3/20 0.50
ALDH1A1 P00352 2/20 0.50
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50
HDAC3 O15379 1/20 0.50
HDAC4 P56524 1/20 0.50
HDAC1 Q13547 1/20 0.50
HDAC7 Q8WUI4 1/20 0.50
HDAC2 Q92769 1/20 0.50
HDAC10 Q969S8 1/20 0.50
HDAC11 Q96DB2 1/20 0.50
HDAC8 Q9BY41 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12781878 0.95 MEN1 (0.70) MEN1KMT2AHSD17B10LMNATDP1
SCHEMBL9352830 0.89 MEN1 (0.65) MEN1KMT2AHSD17B10LMNATDP1
SCHEMBL9521635 0.89 MEN1 (0.65) MEN1KMT2AHSD17B10LMNATDP1
SCHEMBL13061716 0.87 LMNA (0.76) MEN1KMT2AHSD17B10LMNATDP1
SCHEMBL2381677 0.85 MEN1 (0.59) MEN1KMT2AHSD17B10LMNATDP1
SCHEMBL9452351 0.85 MEN1 (0.59) MEN1KMT2AHSD17B10LMNATDP1
SCHEMBL5690802 0.85 MEN1 (0.59) MEN1KMT2AHSD17B10LMNATDP1
SCHEMBL30487756 0.85 MEN1 (0.59) MEN1KMT2AHSD17B10LMNATDP1
SCHEMBL14992464 0.85 KMT2A (0.59) MEN1KMT2AHSD17B10LMNATDP1
SCHEMBL3071609 0.84 LMNA (0.71) MEN1KMT2AHSD17B10LMNATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 256 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022221942-A1 PREVENTION OF DRUG DIVERSION BETTERLIFE PHARMA INC. (CA) 2022-10-27 WO claimed
CN-104583182-A Compositions and methods for treatment of mucositis CELLIX BIO PRIVATE LTD 2015-04-29 CN claimed
US-20260108493-A1 COMPOSITIONS COMPRISING A SEROTONERGIC TRYPTAMINE COMPOUND CAAMTECH, INC. (US) 2026-04-23 US disclosed
US-20260108544-A1 TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH TURTLE BEAR HOLDINGS LLC (US) 2026-04-23 US disclosed
EP-4720030-A1 ASYMMETRIC PHENYLALKYLAMINES Alexander Shulgin Research Institute, Inc. (US) 2026-04-08 EP disclosed
US-20260092034-A1 7-AZAINDOLE ANALOGS AND METHODS OF TREATING NEUROLOGICAL DISORDERS USING THE SAME KULEON LLC (US) 2026-04-02 US disclosed
US-12570602-B2 Selective serotonin receptor modulators and methods of making and using the same Park City Bio, LLC (US) 2026-03-10 US disclosed
US-12564560-B1 Selective serotonin receptor modulators and methods of making and using the same Park City Bio, LLC (US) 2026-03-03 US disclosed
US-20260048048-A1 TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH TURTLE BEAR HOLDINGS LLC (US) 2026-02-19 US disclosed
EP-4673127-A1 DEUTERATED AND FLUORINATED EMPATHOGENS Alexander Shulgin Research Institute, Inc. (US) 2026-01-07 EP disclosed
EP-4673430-A2 PHENYLALKYLAMINE PRODRUGS Alexander Shulgin Research Institute, Inc. (US) 2026-01-07 EP disclosed
US-5110808-A Aldose reductase inhibitors; peripheral effects of diabetes and galactosemia IMPERIAL CHEMICAL INDUSTRIES, PLC (GB) 1992-05-05 US disclosed
EP-0469887-A1 Acetamide derivatives ZENECA LIMITED (GB) 1992-02-05 EP disclosed
EP-0469888-A1 Amidobenzenes IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-02-05 EP disclosed
EP-0469889-A1 (p-Carbonylaminophenyl)-sulphonyl-nitromethane derivatives ZENECA LIMITED (GB) 1992-02-05 EP disclosed
EP-0408713-A1 PHENYLSULPHONE DERIVATIVES. ICI PLC (GB) 1991-01-23 EP disclosed
WO-1990008761-A1 PHENYLSULPHONE DERIVATIVES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-08-09 WO disclosed
US-4600797-A NITRATING AN AMINOBENZENE WHICH HAS A PROTECTEDD AMINO GROUP BAYER AKTIENGESELLSCHAFT (DE) 1986-07-15 US disclosed
EP-0049711-B1 PROCESS FOR THE PRODUCTION OF NITRO-AMINO-BENZENES BAYER AG (DE) 1984-02-29 EP disclosed
EP-0049711-A1 Process for the production of nitro-amino-benzenes BAYER AG (DE) 1982-04-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092034-A1 7-AZAINDOLE ANALOGS AND METHODS OF TREATING NEUROLOGICAL DISORDERS USING THE SAME HTR2C, HTR7, HTR6 MEN1 3416/4885KMT2A 1166/4885HSD17B10 1289/4885
US-20260048048-A1 TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH HTR1B, HTR6, BDNF MEN1 2415/4885KMT2A 3388/4885HSD17B10 3350/4885
US-20260108493-A1 COMPOSITIONS COMPRISING A SEROTONERGIC TRYPTAMINE COMPOUND ADRA2C, ADRB3, ADRA2B MEN1 2766/4885KMT2A 827/4885HSD17B10 2410/4885
US-12570602-B2 Selective serotonin receptor modulators and methods of making and using the same HTR1D, HTR1A, HTR4 MEN1 3949/4885KMT2A 3859/4885HSD17B10 1392/4885
US-12564560-B1 Selective serotonin receptor modulators and methods of making and using the same HTR5A, HTR1A, HTR1D MEN1 3142/4885KMT2A 3491/4885HSD17B10 3711/4885
US-20260108544-A1 TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH HTR1B, HTR6, BDNF MEN1 1743/4885KMT2A 3294/4885HSD17B10 3069/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.