Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NEU3 | Q9UQ49 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | KLK1 | P06870 | 1/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24022836 | 0.85 | HDAC1 (0.62) | NEU3HDAC1HDAC6KLK1KLK5 | |
| SCHEMBL24022830 | 0.79 | MKNK1 (0.38) | NEU3KLK1KLK5ALDH1A1HPGD | |
| SCHEMBL24039027 | 0.78 | NEU3 (0.48) | NEU3KMT2AHDAC1HDAC6KLK1 | |
| SCHEMBL24022749 | 0.78 | PRSS1 (0.48) | KMT2AMEN1ALDH1A1HPGDMAPT | |
| SCHEMBL7903346 | 0.75 | KLK1 (0.56) | NEU3KMT2AMEN1HDAC1HDAC6 | |
| SCHEMBL7894919 | 0.75 | KMT2A (0.53) | NEU3KMT2AMEN1HDAC1HDAC6 | |
| SCHEMBL3362895 | 0.74 | ALDH1A1 (0.55) | NEU3KMT2AMEN1HDAC1HDAC6 | |
| SCHEMBL30275453 | 0.74 | ALDH1A1 (0.55) | NEU3KMT2AMEN1HDAC1HDAC6 | |
| SCHEMBL24022759 | 0.74 | MEN1 (0.44) | KMT2AMEN1ALDH1A1HPGDMAPT | |
| SCHEMBL3586872 | 0.73 | NEU3 (0.58) | NEU3KMT2AMEN1HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021228992-A1 | NUCLIDE LABELLED H-TETRAZINES AND USE THEREOF FOR PET AND SPECT PRETARGETED IMAGING AND RADIONUCLIDE THERAPY | RIGSHOSPITALET (DK) | 2021-11-18 | — | — | WO | disclosed |
| EP-3909944-A1 | NUCLIDE LABELLED H-TETRAZINES AND USE THEREOF FOR PET AND SPECT PRETARGETED IMAGING AND RADIONUCLIDE THERAPY | Rigshospitalet (DK) | 2021-11-17 | — | — | EP | disclosed |