Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | NEU3 | Q9UQ49 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | GPR52 | Q9Y2T5 | 3/20 | 0.34 |
| ▸ | NNMT | P40261 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.33 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24039027 | 0.87 | NEU3 (0.48) | NEU3MAPTHPGDNPC1SMN1; SMN2 | |
| SCHEMBL24022749 | 0.83 | PRSS1 (0.48) | MAPTHPGDNPC1SMN1; SMN2RAB9A | |
| SCHEMBL22043759 | 0.83 | DGAT1 (0.46) | NEU3KLK1KLK5 | |
| SCHEMBL24022841 | 0.79 | NEU3 (0.46) | NEU3MAPTHPGDNPC1RAB9A | |
| SCHEMBL22044394 | 0.77 | RECQL (0.45) | MAPTNPC1RAB9APDE4DLMNA | |
| SCHEMBL24022848 | 0.76 | HDAC1 (0.50) | MAPTNPC1SMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL22043753 | 0.76 | EPHX2 (0.39) | NEU3HPGDRAB9AALDH1A1LMNA | |
| SCHEMBL24022755 | 0.76 | NEU3 (0.46) | NEU3HTT | |
| SCHEMBL2128609 | 0.75 | PARP1 (0.52) | MKNK1MKNK2SMN1; SMN2NNMTBRD4 | |
| SCHEMBL22043785 | 0.75 | KDM4E (0.42) | NEU3MAPTHPGDSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021228992-A1 | NUCLIDE LABELLED H-TETRAZINES AND USE THEREOF FOR PET AND SPECT PRETARGETED IMAGING AND RADIONUCLIDE THERAPY | RIGSHOSPITALET (DK) | 2021-11-18 | — | — | WO | disclosed |
| EP-3909944-A1 | NUCLIDE LABELLED H-TETRAZINES AND USE THEREOF FOR PET AND SPECT PRETARGETED IMAGING AND RADIONUCLIDE THERAPY | Rigshospitalet (DK) | 2021-11-17 | — | — | EP | disclosed |