Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GSK3A | P49840 | 2/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | PAK4 | O96013 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20669564 | 0.80 | ALDH1A1 (0.39) | ALDH1A1KDM4ESMN1; SMN2GAALMNA | |
| SCHEMBL24369218 | 0.78 | ALDH1A1 (0.37) | ALDH1A1KDM4ESMN1; SMN2POLBPABPC1 | |
| SCHEMBL28402473 | 0.76 | ALDH1A1 (0.40) | ALDH1A1KDM4ESMN1; SMN2POLBGAA | |
| SCHEMBL24023373 | 0.75 | DGAT1 (0.39) | HSD11B1LMNAGSK3AGSK3BMAPK1 | |
| SCHEMBL21201306 | 0.74 | ALDH1A1 (0.39) | ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL9952026 | 0.74 | MEN1 (0.44) | ALDH1A1KDM4ESMN1; SMN2EGFRERBB3 | |
| SCHEMBL30163570 | 0.74 | MEN1 (0.44) | ALDH1A1KDM4ESMN1; SMN2EGFRERBB3 | |
| SCHEMBL24023234 | 0.73 | PIK3CA (0.42) | ALDH1A1SMN1; SMN2MEN1MAPK1KMT2A | |
| SCHEMBL16737338 | 0.71 | CYP4F2 (0.45) | ALDH1A1KDM4ESMN1; SMN2EGFRERBB3 | |
| SCHEMBL14064840 | 0.71 | PTGDR2 (0.44) | ALDH1A1KDM4ESMN1; SMN2POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210353607-A1 | PI3K INHIBITORS AND USES THEREOF | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2021-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210353607-A1 | PI3K INHIBITORS AND USES THEREOF | PIK3CA, AKT3, GSK3B | HSD11B1 1142/4885ALDH1A1 2009/4885KDM4E 4543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.