Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | KYNU | Q16719 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 2/20 | 0.51 |
| ▸ | CTSB | P07858 | 2/20 | 0.51 |
| ▸ | CTSS | P25774 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 1/20 | 0.50 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.49 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | TACR1 | P25103 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28586890 | 1.00 | ALDH1A1 (0.57) | ALDH1A1ALOX15MEN1KMT2AKYNU | |
| SCHEMBL14562452 | 0.93 | ITGA4 (0.56) | ALDH1A1ALOX15MEN1KMT2ACTSL | |
| SCHEMBL14562475 | 0.93 | ITGA4 (0.56) | ALDH1A1ALOX15MEN1KMT2ACTSL | |
| SCHEMBL28577401 | 0.88 | ALDH1A1 (0.56) | ALDH1A1ALOX15MEN1KMT2AKYNU | |
| SCHEMBL28577399 | 0.88 | ALDH1A1 (0.56) | ALDH1A1ALOX15MEN1KMT2AKYNU | |
| SCHEMBL5162574 | 0.85 | ALDH1A1 (0.56) | ALDH1A1ALOX15MEN1KMT2AKYNU | |
| SCHEMBL31628222 | 0.84 | ALDH1A1 (0.57) | ALDH1A1ALOX15MEN1KMT2AKYNU | |
| SCHEMBL5887270 | 0.83 | ALDH1A1 (0.65) | ALDH1A1ALOX15MEN1KMT2AKYNU | |
| SCHEMBL5887268 | 0.83 | ALDH1A1 (0.65) | ALDH1A1ALOX15MEN1KMT2AKYNU | |
| SCHEMBL7151822 | 0.83 | ALDH1A1 (0.74) | ALDH1A1ALOX15MEN1KMT2AKYNU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109704996-B | Method for preparing 3-halogenated-N-protected-L-tyrosine methyl ester | 安阳工学院 | 2021-06-08 | — | — | CN | disclosed |
| US-20130244929-A1 | BRIDGED LIPOGLYCOPEPTIDES THAT POTENTIATE THE ACTIVITY OF BETA-LACTAM ANTIBACTERIALS | MERCK SHARP & DOHME CORP. | 2013-09-19 | — | — | US | disclosed |
| WO-2011112441-A1 | BRIDGED LIPOGLYCOPEPTIDES THAT POTENTIATE THE ACTIVITY OF BETA-LACTAM ANTIBACTERIALS | MERCK SHARP & DOHME CORP. (US) | 2011-09-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130244929-A1 | BRIDGED LIPOGLYCOPEPTIDES THAT POTENTIATE THE ACTIVITY OF BETA-LACTAM ANTIBACTERIALS | SPPL2B, ENGASE, PEPD | ALDH1A1 3225/4885ALOX15 1719/4885MEN1 2299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.