Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 1/20 | 0.56 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | FPR2 | P25090 | 1/20 | 0.54 |
| ▸ | ITGB3 | P05106 | 9/20 | 0.52 |
| ▸ | ITGAV | P06756 | 1/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.52 |
| ▸ | CTSL | P07711 | 2/20 | 0.51 |
| ▸ | CTSB | P07858 | 2/20 | 0.51 |
| ▸ | CTSS | P25774 | 2/20 | 0.51 |
| ▸ | CTSK | P43235 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14562475 | 1.00 | ITGA4 (0.56) | ITGA4ITGB7MEN1KMT2AALDH1A1 | |
| SCHEMBL2402472 | 0.93 | ALDH1A1 (0.57) | ITGA4ITGB7MEN1KMT2AALDH1A1 | |
| SCHEMBL28586890 | 0.93 | ALDH1A1 (0.57) | ITGA4ITGB7MEN1KMT2AALDH1A1 | |
| SCHEMBL8219255 | 0.88 | ITGB3 (0.51) | ITGA4ITGB7ALDH1A1ALOX15ITGB3 | |
| SCHEMBL9825306 | 0.85 | ITGA4 (0.57) | ITGA4ITGB7MEN1KMT2AALDH1A1 | |
| SCHEMBL8586541 | 0.85 | FOLH1 (0.58) | ITGB3ITGAVITGA2BCTSLCTSB | |
| SCHEMBL8582379 | 0.85 | CTSL (0.55) | ALDH1A1ALOX15ITGB3ITGAVITGA2B | |
| SCHEMBL29107666 | 0.84 | ITGA4 (0.56) | ITGA4ITGB7MEN1KMT2AALDH1A1 | |
| SCHEMBL29107785 | 0.83 | ALDH1A1 (0.64) | ITGA4ITGB7MEN1KMT2AALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL4097339 | 0.82 | ITGB3 (0.55) | ITGA4ITGB7MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2544702-A1 | BRIDGED LIPOGLYCOPEPTIDES THAT POTENTIATE THE ACTIVITY OF BETA-LACTAM ANTIBACTERIALS | Merck Sharp & Dohme Corp. (US) | 2013-01-16 | — | — | EP | disclosed |