Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.33 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.33 |
| ▸ | TKT | P29401 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL353361 | 0.81 | KDM4E (0.59) | CYP1A2KDM4EMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL2085063 | 0.80 | GABRA1 (0.42) | CYP1A2KDM4EMAPTCYP3A4CYP2C8 | |
| SCHEMBL24260237 | 0.77 | KDM4E (0.39) | CYP1A2KDM4EMAPTCYP2C9CYP2C19 | |
| SCHEMBL353255 | 0.77 | MAPT (0.44) | CYP1A2KDM4EMAPTCYP3A4CYP2C19 | |
| SCHEMBL6115316 | 0.77 | TRIM24 (0.39) | CYP1A2KDM4EMAPTALDH1A1TRIM24 | |
| SCHEMBL8309858 | 0.75 | TRIM24 (0.42) | CYP1A2KDM4EMAPTALDH1A1TRIM24 | |
| SCHEMBL3296819 | 0.75 | KDM4E (0.42) | CYP1A2KDM4EMAPTALDH1A1HTT | |
| SCHEMBL4031836 | 0.74 | NPSR1 (0.34) | CYP1A2KDM4EMAPTCYP3A4CYP2C8 | |
| Benzene SCHEMBL11824212 | 0.74 | TRIM24 (0.37) | CYP1A2KDM4EMAPTSLC13A5ALDH1A1 | |
| SCHEMBL4030524 | 0.73 | MAOA (0.41) | KDM4EALDH1A1P2RX7NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210356473-A1 | SOLID-PHASE N-TERMINAL PEPTIDE CAPTURE AND RELEASE | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2021-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210356473-A1 | SOLID-PHASE N-TERMINAL PEPTIDE CAPTURE AND RELEASE | ANPEP, MAX, DNPEP | CYP1A2 4885/4885KDM4E 4100/4885MAPT 2741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.